7S-NERVE GROWTH FACTOR, MOUSE

7S-NERVE GROWTH FACTOR, MOUSE Structure
7S-NERVE GROWTH FACTOR, MOUSE structure
Common Name 7S-NERVE GROWTH FACTOR, MOUSE
CAS Number 9061-61-4 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS USA Flash Point N/A

Pdcd4 modulates markers of macrophage alternative activation and airway remodeling in antigen-induced pulmonary inflammation.

J. Leukoc. Biol. 96(6) , 1065-75, (2014)

Pdcd4 has been known as a tumor-suppressor gene initially and is up-regulated during apoptosis. Surprisingly, we found that Pdcd4 was differentially expressed in the lung from E3 rats with AIPI, an animal model for asthma, but the precise role of Pdcd4 in AIP...

Adjuvant neurotrophic factors in peripheral nerve repair with chondroitin sulfate proteoglycan-reduced acellular nerve allografts.

J. Surg. Res. 193(2) , 969-77, (2015)

Acellular nerve allografts are now standard tools in peripheral nerve repair because of decreased donor site morbidity and operative time savings. Preparation of nerve allografts involves several steps of decellularization and modification of extracellular ma...

Nerve growth factor promotes expression of novel genes in intervertebral disc cells that regulate tissue degradation: Laboratory investigation.

J. Neurosurg. Spine 21(4) , 653-61, (2014)

Increased neurotrophin activity in degenerative intervertebral discs (IVDs) is one potential cause of chronic low-back pain (LBP). The aim of the study was to assess if nerve growth factor (NGF) might alter gene expression of IVD cells and contribute to disc ...

A sympathetic neuron autonomous role for Egr3-mediated gene regulation in dendrite morphogenesis and target tissue innervation.

J. Neurosci. 33(10) , 4570-83, (2013)

Egr3 is a nerve growth factor (NGF)-induced transcriptional regulator that is essential for normal sympathetic nervous system development. Mice lacking Egr3 in the germline have sympathetic target tissue innervation abnormalities and physiologic sympathetic d...

Extracellular pH and neuronal depolarization serve as dynamic switches to rapidly mobilize trkA to the membrane of adult sensory neurons.

J. Neurosci. 33(19) , 8202-15, (2013)

Activation of the nerve growth factor (NGF) receptor trkA and tissue acidosis are critically linked to inflammation-associated nociceptor sensitization. This study explored how increased acidity is linked to sensory neuron sensitization to NGF. Adult Wistar r...

Epidermal fatty acid-binding protein protects nerve growth factor-differentiated PC12 cells from lipotoxic injury.

J. Neurochem. 132(1) , 85-98, (2015)

Epidermal fatty acid-binding protein (E-FABP/FABP5/DA11) binds and transport long-chain fatty acids in the cytoplasm and may play a protecting role during neuronal injury. We examined whether E-FABP protects nerve growth factor-differentiated PC12 cells (NGFD...

TNFα reverse signaling promotes sympathetic axon growth and target innervation.

Nat. Neurosci. 16(7) , 865-73, (2013)

Reverse signaling via members of the tumor necrosis factor (TNF) superfamily controls multiple aspects of immune function. Here we document TNFα reverse signaling in the nervous system to our knowledge for the first time and show that it has a crucial role in...

Bordetella pertussis infection or vaccination substantially protects mice against B. bronchiseptica infection.

PLoS ONE 4(8) , e6778, (2009)

Although B. bronchiseptica efficiently infects a wide range of mammalian hosts and efficiently spreads among them, it is rarely observed in humans. In contrast to the many other hosts of B. bronchiseptica, humans are host to the apparently specialized pathoge...

Etifoxine provides benefits in nerve repair with acellular nerve grafts.

Muscle Nerve 50(2) , 235-43, (2014)

Acellular nerve grafts are good candidates for nerve repair, but the clinical outcome of grafting is not always satisfactory. We investigated whether etifoxine could enhance nerve regeneration.Seventy-two Sprague-Dawley rats were divided into 3 groups: (1) au...

ProNGF promotes neurite growth from a subset of NGF-dependent neurons by a p75NTR-dependent mechanism.

Development 140(10) , 2108-17, (2013)

The somatosensory and sympathetic innervation of the vertebrate head is derived principally from the neurons of trigeminal and superior cervical ganglia (SCG), respectively. During development, the survival of both populations of neurons and the terminal grow...