C5, HUMAN
C5, HUMAN structure
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Common Name | C5, HUMAN | ||
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| CAS Number | 80295-53-0 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria.
N. Engl. J. Med. 350 , 552-559, (2004) Paroxysmal nocturnal hemoglobinuria (PNH) arises from a somatic mutation of the PIG-A gene in a hematopoietic stem cell and the subsequent production of blood cells with a deficiency of surface proteins that protect the cells against attack by the complement ... |
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Achievements and limitations of complement inhibition by eculizumab in paroxysmal nocturnal hemoglobinuria: the role of complement component 3.
Mini Rev. Med. Chem. 11 , 528-535, (2011) Paroxysmal nocturnal hemoglobinuria (PNH) is a hematological disorder characterized by complementmediated hemolytic anemia, thrombophilia and bone marrow failure. The clinical hallmark of PNH is evident chronic hemolysis due to the absence of the complement r... |
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The role of complement inhibition in PNH. Hillmen P.
Hematology Am. Soc. Hematol. Educ. Program 2008(1) , 116-123, (2008)
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