GW-8510
GW-8510 structure
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Common Name | GW-8510 | ||
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| CAS Number | 222036-17-1 | Molecular Weight | 449.51 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H15N5O3S2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Cytoplasmic nucleophosmin has elevated T199 phosphorylation upon which G2/M phase progression is dependent.
Sci. Rep. 5 , 11777, (2015) The cytoplasmic mutant of nucleophosmin (NPMc) is found approximately in one-third of acute myeloid leukemia (AML) cases and is highly associated with normal karyotype. Whereas previous studies have focused on wtNPM in centrosome duplication, we further eluci... |
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Glycogen synthase kinase 3 is a potential drug target for African trypanosomiasis therapy.
Antimicrob. Agents Chemother. 52(10) , 3710-7, (2008) Development of a safe, effective, and inexpensive therapy for African trypanosomiasis is an urgent priority. In this study, we evaluated the validity of Trypanosoma brucei glycogen synthase kinase 3 (GSK-3) as a potential drug target. Interference with the RN... |
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