DL-Homocysteine
DL-Homocysteine structure
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Common Name | DL-Homocysteine | ||
|---|---|---|---|---|
| CAS Number | 454-29-5 | Molecular Weight | 135.185 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 299.7±35.0 °C at 760 mmHg | |
| Molecular Formula | C4H9NO2S | Melting Point | 232-233 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 135.0±25.9 °C | |
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Activation of AMP-activated protein kinase protects against homocysteine-induced apoptosis of osteocytic MLO-Y4 cells by regulating the expressions of NADPH oxidase 1 (Nox1) and Nox2.
Bone 77 , 135-41, (2015) Elevated plasma homocysteine (Hcy) level is associated with the risk of osteoporotic fracture. While Hcy increases oxidative stress, AMP-activated protein kinase (AMPK) activation ameliorates it. This study aimed to investigate whether Hcy induces apoptosis o... |
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Protective effect of sulfurous water in peripheral blood mononuclear cells of Alzheimer's disease patients.
Life Sci. 132 , 61-7, (2015) One of the main features of sulfurous water (SW) is the presence of hydrogen sulfide (H2S), which confers its antioxidant activity. Since oxidative stress plays an important role in Alzheimer's disease (AD) we hypothesize that SW could have a protective effec... |
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Sulfur amino acid metabolism in Zucker diabetic fatty rats.
Biochem. Pharmacol. 96 , 256-66, (2015) The present study was aimed to investigate the metabolomics of sulfur amino acids in Zucker diabetic fatty (ZDF) rats, an obese type 2 diabetic animal model. Plasma levels of total cysteine, homocysteine and methionine, but not glutathione (GSH) were markedly... |
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Tween 20-stabilized gold nanoparticles combined with adenosine triphosphate-BODIPY conjugates for the fluorescence detection of adenosine with more than 1000-fold selectivity.
Anal. Chim. Acta 857 , 64-70, (2015) This study describes the development of a simple, enzyme-free, label-free, sensitive, and selective system for detecting adenosine based on the use of Tween 20-stabilized gold nanoparticles (Tween 20-AuNPs) as an efficient fluorescence quencher for boron dipy... |
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Liquid Chromatography with Amperometric Detection at a Silver Based Detector for the Determination of Thiocompounds: Application to the Assay of Thiopurine Antimetabolites in Urine.
Anal. Chem. 87 , 6730-5, (2015) A silver amperometric detector coupled to liquid chromatography (LC) was used for the determination of 6-thioguanine (6-TG) and two of its metabolites, thiouric acid (TU) and 2-amino-6-mercaptopurine riboside (6-TGR). The silver detector coupled to LC operate... |
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Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis-mass spectrometry.
Electrophoresis 35(23) , 3321-30, (2014) There is high interest in the discovery of early diagnostic biomarkers of Alzheimer's disease, for which metabolomics exhibits a great potential. In this work, a metabolomic approach based on ultrafiltration and analysis by CE-MS has been used to obtain repre... |
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Selenitetriglycerides-Redox-active agents.
Pharmacol. Rep. 67(1) , 1-8, (2015) Human prostate cancer (hPCa) is the most commonly diagnosed cancer in elderly men and is the second leading cause of male cancer death. Data from epidemiological, eco-environmental, nutritional prevention and clinical trials suggest that selenium Se(IV) can p... |
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Diagnostic use of cerebral and extracerebral oxysterols.
Clin. Chem. Lab Med. 42(2) , 186-91, (2004) 24S-Hydroxycholesterol (24OHC) and 27-hydroxycholesterol (27OHC) are two structurally similar oxysterols of different origins--the former almost exclusively formed in the brain and the latter formed to a lesser extent in the brain than in most other organs. H... |
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Levels of 7-oxocholesterol in cerebrospinal fluid are more than one thousand times lower than reported in multiple sclerosis.
J. Lipid Res. 46(2) , 191-5, (2005) In a recent publication [Diestel, A., O. Aktas, D. Hackel, I. Hake, S. Meier, C. S. Raine, R. Nitsch, F. Zipp, and O. Ullrich. 2003. Activation of microglial poly (ADP-ribose)-polymerase-1 by cholesterol breakdown products during neuroinflammation: a link bet... |
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Disruption of thiol homeostasis and nitrosative stress in the cerebrospinal fluid of patients with active multiple sclerosis: evidence for a protective role of acetylcarnitine.
Neurochem. Res. 28(9) , 1321-8, (2003) Recent studies suggest that NO and its reactive derivative peroxynitrite are implicated in the pathogenesis of multiple sclerosis (MS). Patients dying with MS demonstrate increased astrocytic inducible nitric oxide synthase activity, as well as increased leve... |