Spermine

Spermine Structure
Spermine structure
Common Name Spermine
CAS Number 9015-13-8 Molecular Weight 202.340
Density 0.9±0.1 g/cm3 Boiling Point 308.4±0.0 °C at 760 mmHg
Molecular Formula C10H26N4 Melting Point N/A
MSDS Chinese USA Flash Point 175.6±22.6 °C

Optimized Treatment of Heparinized Blood Fractions to Make Them Suitable for Analysis.

Biopreserv. Biobank. 13 , 287-95, (2015)

It has been known for decades that many cytokines, such as IL-2, IL-6, and IL-12, bind to heparin. Even though some enzyme-linked immunosorbent assays (ELISA) use antibody-recognizing epitopes not affected by this binding, ELISA manufacturers often warn that ...

A modified thromboelastographic method for monitoring c7E3 Fab in heparinized patients.

Anesth. Analg. 84 , 31-38, (1997)

The monoclonal antibody, c7E3 Fab, binds to the platelet surface fibrinogen receptor (GPIIb/IIIa), inhibiting platelet aggregation and clot retraction. We performed an in vitro study to assess the ability of a modification of the thromboelastograph (MTEG) to ...

Improved high-performance liquid chromatographic method to estimate aminosugars and its application to glycosaminoglycan determination in plasma and serum.

J. Chromatogr. B. Biomed. Sci. Appl. 765 , 151-160, (2001)

An improved isocratic high-performance liquid chromatography (HPLC) method for the analysis of L-(-)-fucose. D-(+)-galactosamine, D-(+)-glucosamine, D-(+)-galactose, obtained by hydrolysis of glycosaminoglycans (GAGs) and D-(+)-glucose and D-(+)-mannose is de...

Characteristics of the interactions between acid glycosaminoglycans and proteins in normal human plasma as revealed by the behaviour of the protein-polysaccharide complexes in ultrafiltration and chromatographic procedures.

Clin. Chim. Acta 206 , 167-180, (1992)

Acid glycosaminoglycans were isolated from normal human plasma: (a) following fractionation of plasma (with protease inhibitors) on Sephadex G-200; (b) by ultrafiltration through membranes with retention of molecules above 50 kDa, with and without previous ad...

Monitoring heparin therapy: relationships between the activated partial thromboplastin time and heparin assays based on ex-vivo heparin samples.

Thromb. Haemost. 63(1) , 16-23, (1990)

Five different APTT-reagents, two amidolytic anti-IIa assays, one amidolytic anti-Xa assay, and one coagulometric anti-Xa/anti-IIa assay were used to assess the effect of heparin in patients treated for venous thromboembolic disease. Good correlations were ob...

Enzymatic elimination of heparin from plasma for activated partial thromboplastin time and prothrombin time testing.

Blood Coagul. Fibrinolysis 4(4) , 635-8, (1993)

The prolongation of the APTT and PT by heparin can be neutralized by treating the plasma with heparinase or with certain anion-exchangers. The purpose of the present study was to assess the effectiveness of a new commercial heparinase reagent. Heparinase (Hep...

Clinical sample investigation (CSI) hematology: pinpointing the precise onset of heparin-induced thrombocytopenia (HIT).

J. Thromb. Haemost. 5(3) , 636-7, (2007)