POLYINOSINIC ACID (5') POTASSIUM SALT

POLYINOSINIC ACID (5') POTASSIUM SALT Structure
POLYINOSINIC ACID (5') POTASSIUM SALT structure
Common Name POLYINOSINIC ACID (5') POTASSIUM SALT
CAS Number 26936-41-4 Molecular Weight 386.296
Density N/A Boiling Point N/A
Molecular Formula C10H12KN4O8P Melting Point N/A
MSDS USA Flash Point N/A

Mutational analysis of vaccinia virus E3 protein: the biological functions do not correlate with its biochemical capacity to bind double-stranded RNA.

J. Virol. 89(10) , 5382-94, (2015)

Vaccinia E3 protein has the biochemical capacity of binding to double-stranded RNA (dsRNA). The best characterized biological functions of the E3 protein include its host range function, suppression of cytokine expression, and inhibition of interferon (IFN)-i...

Toll-like receptors 2 and 3 agonists differentially affect oligodendrocyte survival, differentiation, and myelin membrane formation.

J. Neurosci. Res. 90(2) , 388-98, (2011)

Toll-like receptors (TLRs) play a key role in controlling innate immune responses to a wide variety of pathogen-associated molecules as well as endogenous signals. In addition, TLR expression within nonimmune cells has been recognized as as modulator of cell ...

Toll-like receptor 3-mediated tumor invasion in head and neck cancer.

Oral Oncol. 48(3 , 226-32, (2011)

Chronic inflammation associated with some infectious agents can lead to cancer. The Toll-like receptor (TLR) family is one of the largest and best-studied families of pathogen-associated molecular patterns. TLR3 recognizes double-stranded RNA and is a major e...

Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1.

J. Biol. Chem. 286(52) , 44750-63, (2011)

The induction of β-interferon (IFN-β) is a key anti-viral response to infection by RNA viruses. Virus-induced expression of IFN-β requires the co-operative action of the transcription factors IRF-3/7, NF-κB, and ATF-2/c-Jun on the IFN-β promoter leading to th...

Activation of chemokine and inflammatory cytokine response in HCV-infected hepatocytes depends on TLR3 sensing of HCV dsRNA intermediates. Li K, Li NL, Wei D, Pfeffer SR, et al.

Hepatology 55(3) , 666-75, (2011)

CAF05: cationic liposomes that incorporate synthetic cord factor and poly(I:C) induce CTL immunity and reduce tumor burden in mice. Hansen J, Lindenstrøm T, et al.

Cancer Immunol. Immunother. , (2011)

Overlapping and distinct roles of GRK5 in TLR2-, and TLR3-induced inflammatory response in vivo. Packiriswamy N, Parvataneni S, Parameswaran N.

Cell. Immunol. , 107-11, (2011)