Adenosine-3'-monophosphate Sodium Salt

Adenosine-3'-monophosphate Sodium Salt Structure
Adenosine-3'-monophosphate Sodium Salt structure
Common Name Adenosine-3'-monophosphate Sodium Salt
CAS Number 4958-39-8 Molecular Weight 391.185
Density N/A Boiling Point N/A
Molecular Formula C10H12N5Na2O7P Melting Point N/A
MSDS N/A Flash Point N/A

2',3'-cAMP hydrolysis by metal-dependent phosphodiesterases containing DHH, EAL, and HD domains is non-specific: Implications for PDE screening.

Biochem. Biophys. Res. Commun. 398 , 500-505, (2010)

The recent report of 2',3'-cAMP isolated from rat kidney is the first proof of its biological existence, which revived interest in this mysterious molecule. 2',3'-cAMP serves as an extracellular adenosine source, but how it is degraded remains unclear. Here, ...

Extracellular 2,3-cyclic adenosine monophosphate is a potent inhibitor of preglomerular vascular smooth muscle cell and mesangial cell growth [corrected].

Hypertension 56 , 151-158, (2010)

Recently we discovered that intact kidneys release into the extracellular compartment 2',3'-cAMP (a positional isomer of 3',5'-cAMP with unknown pharmacology) and metabolize 2',3'-cAMP to 2'-AMP, 3'-AMP, and adenosine. Because adenosine inhibits growth of vas...

2′-AMP and 3′-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. Jackson EK, Gillespie DG, Dubey RK.

J. Pharmacol. Exp. Ther. 337 , 4440450, (2011)