MDL 105519

MDL 105519 Structure
MDL 105519 structure
Common Name MDL 105519
CAS Number 161230-88-2 Molecular Weight 376.190
Density 1.6±0.1 g/cm3 Boiling Point 601.3±55.0 °C at 760 mmHg
Molecular Formula C18H11Cl2NO4 Melting Point N/A
MSDS USA Flash Point 317.5±31.5 °C

Pharmacological characterization of MDL 105,519, an NMDA receptor glycine site antagonist.

Eur. J. Pharmacol. 323 , 181-192, (1997)

MDL 105,519, (E)-3-(2-phenyl-2-carboxyethenyl)-4,6-dichloro-1 H-indole-2-carboxylic acid, is a potent and selective inhibitor of [3H]glycine binding to the NMDA receptor. MDL 105,519 inhibits NMDA (N-methyl-D-aspartate)-dependent responses including elevation...