Chondroitin sulfate B sodium salt
Chondroitin sulfate B sodium salt structure
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Common Name | Chondroitin sulfate B sodium salt | ||
|---|---|---|---|---|
| CAS Number | 54328-33-5 | Molecular Weight | 1526.03 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Chondroitin Sulfate is the Primary Receptor for a Peptide-Modified AAV That Targets Brain Vascular Endothelium In Vivo.
Mol. Ther. Nucleic Acids 3 , e202, (2014) Recently, we described a peptide-modified AAV2 vector (AAV-GMN) containing a capsid-displayed peptide that directs in vivo brain vascular targeting and transduction when delivered intravenously. In this study, we sought to identify the receptor that mediates ... |
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Non-destructive monitoring of viability in an ex vivo organ culture model of osteochondral tissue.
Eur. Cell. Mater. 29 , 356-69; discussion 369, (2015) Organ culture is an increasingly important tool in research, with advantages over monolayer cell culture due to the inherent natural environment of tissues. Successful organ cultures must retain cell viability. The aim of this study was to produce viable and ... |
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Molecular interplay between endostatin, integrins, and heparan sulfate.
J. Bacteriol. 284 , 22029-40, (2009) Endostatin is an endogenous inhibitor of angiogenesis. Although several endothelial cell surface molecules have been reported to interact with endostatin, its molecular mechanism of action is not fully elucidated. We used surface plasmon resonance assays to c... |
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Sulfated polysaccharides promote the assembly of amyloid beta(1-42) peptide into stable fibrils of reduced cytotoxicity.
J. Biol. Chem. 283 , 32471-32483, (2008) The histopathological hallmarks of Alzheimer disease are the self-aggregation of the amyloid beta peptide (Abeta) in extracellular amyloid fibrils and the formation of intraneuronal Tau filaments, but a convincing mechanism connecting both processes has yet t... |
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Modulation of amyloid beta peptide(1-42) cytotoxicity and aggregation in vitro by glucose and chondroitin sulfate.
Curr. Alzheimer Res. 7 , 428-438, (2010) One mechanism leading to neurodegeneration during Alzheimer's disease (AD) is amyloid beta peptide (Abeta)-induced neurotoxicity. Among the factors proposed to potentiate Abeta toxicity is its covalent modification through carbohydrate-derived advanced glycat... |
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Randomization of amyloid-β-peptide(1-42) conformation by sulfonated and sulfated nanoparticles reduces aggregation and cytotoxicity.
Macromol. Biosci. 10 , 1152-1163, (2010) The amyloid-β peptide (Aβ) plays a central role in the mechanism of Alzheimer's disease, being the main constituent of the plaque deposits found in AD brains. Aβ amyloid formation and deposition are due to a conformational switching to a β-enriched secondary ... |
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Immune reactivity to connective tissue antigens in pristane induced arthritis.
J. Rheumatol. 31 , 1497-1505, (2004) Pristane induced arthritis (PIA) is a seropositive experimental murine model that closely resembles rheumatoid arthritis (RA). Immune reactivity to a broad spectrum of autoantigens has been recognized in this disease model. We investigated the specificity of ... |
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Hyaluronidase of bloodsucking insects and its enhancing effect on leishmania infection in mice.
PLoS Negl. Trop. Dis. 2(9) , e294, (2008) Salivary hyaluronidases have been described in a few bloodsucking arthropods. However, very little is known about the presence of this enzyme in various bloodsucking insects and no data are available on its effect on transmitted microorganisms. Here, we studi... |