rimorphin

rimorphin Structure
rimorphin structure
Common Name rimorphin
CAS Number 85006-82-2 Molecular Weight 1570.835
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C74H115N21O17 Melting Point N/A
MSDS USA Flash Point N/A

Hippocampal dynorphin B injections impair spatial learning in rats: a kappa-opioid receptor-mediated effect.

Neuroscience 85 , 375-382, (1998)

The hippocampus plays a central role in the acquisition and storage of information. Long-term potentiation in the mossy fibre pathway to the CA3 region in the hippocampus, an animal model of memory acquisition, is modulated by dynorphin peptides. This study i...

Nuclear opioid receptors activate opioid peptide gene transcription in isolated myocardial nuclei.

J. Biol. Chem. 273 , 13383-13386, (1998)

Opioid-binding sites were identified in highly purified nuclei isolated from hamster ventricular myocardial cells. A significant increase in the maximal binding capacity for a kappa opioid receptor ligand was observed in myocardial nuclei from BIO 14.6 cardio...

Specificity of the dynorphin-processing endoprotease: comparison with prohormone convertases.

J. Neurochem. 72 , 2120-2126, (1999)

The cleavage specificity of a monobasic processing dynorphin converting endoprotease is examined with a series of quench fluorescent peptide substrates and compared with the cleavage specificity of prohormone convertases. A dynorphin B-29-derived peptide, Abz...

Antisense mapping KOR-1: evidence for multiple kappa analgesic mechanisms.

Brain Res. 826 , 289-292, (1999)

In binding assays, both dynorphin B and alpha-neoendorphin are relatively selective for the kappa1b site, unlike U50,488H which has high affinity for both kappa1a and kappa1b sites. In vivo, U50,488H, dynorphin B and alpha-neoendorphin analgesia are reversed ...