Importazole
Importazole structure
|
Common Name | Importazole | ||
|---|---|---|---|---|
| CAS Number | 662163-81-7 | Molecular Weight | 318.415 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 516.8±42.0 °C at 760 mmHg | |
| Molecular Formula | C20H22N4 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 266.3±27.9 °C | |
|
NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane.
EMBO J. 33(16) , 1815-30, (2014) The positioning and the elongation of the mitotic spindle must be carefully regulated. In human cells, the evolutionary conserved proteins LGN/Gαi1-3 anchor the coiled-coil protein NuMA and dynein to the cell cortex during metaphase, thus ensuring proper spin... |
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