APOFERRITIN
APOFERRITIN structure
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Common Name | APOFERRITIN | ||
|---|---|---|---|---|
| CAS Number | 9013-31-4 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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mRNA regulation of cardiac iron transporters and ferritin subunits in a mouse model of iron overload.
Exp. Hematol. 42(12) , 1059-67, (2014) Iron cardiomyopathy is the leading cause of death in iron overload. Men have twice the mortality rate of women, though the cause is unknown. In hemojuvelin-knockout mice, a model of the disease, males load more cardiac iron than females. We postulated that se... |
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Autophagy of metallothioneins prevents TNF-induced oxidative stress and toxicity in hepatoma cells.
Autophagy 11 , 2184-98, (2016) Lysosomal membrane permeabilization (LMP) induced by oxidative stress has recently emerged as a prominent mechanism behind TNF cytotoxicity. This pathway relies on diffusion of hydrogen peroxide into lysosomes containing redox-active iron, accumulated by brea... |
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Molecular weight standards for calibration of gel filtration and sodium dodecyl sulfate-polyacrylamide gel electrophoresis: ferritin and apoferritin.
Anal. Biochem. 16 , 235, (1987) Ferritin and apoferritin are widely used for the calibration of gel filtration columns and sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis and are commercially offered for these purposes as part of molecular weight calibration kits. Many of th... |
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Caged-protein-confined bimetallic structural assemblies with mimetic peroxidase activity.
Small 8(19) , 2948-53, (2012)
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Electron microscopy: Ultrastable gold substrates for electron cryomicroscopy.
Science 346(6215) , 1377-80, (2014) Despite recent advances, the structures of many proteins cannot be determined by electron cryomicroscopy because the individual proteins move during irradiation. This blurs the images so that they cannot be aligned with each other to calculate a three-dimensi... |
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Hereditary hyperferritinemia cataract syndrome as a cause of childhood hyperferritinemia.
J. Pediatr. Hematol. Oncol. 36(5) , e304-6, (2014) A 2-year-old female was presented with high levels of serum ferritin (890 ng/mL) in a routine blood test. Clinical and laboratory investigations excluded the presence of iron overload and secondary causes of hyperferritinemia. A detailed family history and la... |
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H-ferritin overexpression promotes radiation-induced leukemia/lymphoma in mice.
Carcinogenesis 33(11) , 2269-75, (2012) H-ferritin (HF) is a core subunit of the iron storage protein ferritin and is related to the pathogenesis of malignant diseases. HF overexpression is present in human hematologic malignancies, suggesting that HF overexpression may contribute to the developmen... |
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Solid-state electron transport in Mn-, Co-, holo-, and Cu-ferritins: force-induced modulation is inversely linked to the protein conductivity.
J. Colloid. Interface Sci. 388(1) , 282-92, (2012) In this work, solid-state electron transport through the three metal core reconstituted ferritins, namely, Mn(III)-ferritin, Co(III)-ferritin, and Cu(II)-ferritin, has been probed and compared to the electron transport via the naturally-occurring iron-contain... |
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Automatic magnification determination of electron cryomicroscopy images using apoferritin as a standard.
J. Struct. Biol. 180(1) , 243-8, (2012) Interpretation of the structural information in cryomicroscopy images recorded on film or CCD camera requires a precise knowledge of the electron microscope parameters that affect image features such as magnification and defocus. Magnification must be determi... |
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In vivo long-term magnetic resonance imaging activity of ferritin-based magnetic nanoparticles versus a standard contrast agent.
J. Med. Chem. 57(13) , 5686-92, (2014) New long-circulating maghemite nanoparticles of 4 and 6 nm, coated with an apoferritin protein capsid, exhibit useful properties to act as magnetic resonance imaging (MRI) contrast agents. A full in vivo study of the so-called apomaghemites reveals that their... |