Polyadenylic acid potassium salt

Polyadenylic acid potassium salt Structure
Polyadenylic acid potassium salt structure
Common Name Polyadenylic acid potassium salt
CAS Number 26763-19-9 Molecular Weight 385.312
Density N/A Boiling Point N/A
Molecular Formula C10H13KN5O7P Melting Point N/A
MSDS USA Flash Point N/A

RNA Binds to Tau Fibrils and Sustains Template-Assisted Growth.

Biochemistry 54 , 4731-40, (2015)

Tau fibrils are the main proteinacious components of neurofibrillary lesions in Alzheimer disease. Although RNA molecules are sequestered into these lesions, their relationship to Tau fibrils is only poorly understood. Such understanding, however, is importan...

Molecular aspects of small molecules-poly(A) interaction: an approach to RNA based drug design.

Curr. Med. Chem. 16 , 965-987, (2009)

The use of small molecules to specifically control important cellular functions is an area of major current interest at the interface of chemical biology and medicinal chemistry. Recognition of ribonucleic acids (RNA) has emerged more recently as a critical e...

Isoquinoline alkaloids and their binding with polyadenylic acid: potential basis of therapeutic action.

Mini Rev. Med. Chem. 10 , 568-577, (2010)

After fifty years of DNA targeting through intercalators and groove binders and related studies now the current focus is in RNA targeting. Polyadenylic acid [poly(A)] tail of mRNA has been recently established as a potential drug target due to its significant...

Molecular recognition of poly(A) targeting by protoberberine alkaloids: in vitro biophysical studies and biological perspectives.

Mol. Biosyst. 6 , 81-88, (2010)

The use of small molecules to specifically control important cellular functions through binding to nucleic acids is an area of major current interest at the interface of chemical biology and medicinal chemistry. The polyadenylic acid [poly(A)] tail of mRNA ha...

Polyadenylic acid binding on cationic liposomes doped with the non-ionic nucleolipid Lauroyl Uridine. Cuomo F, Ceglie A, Colafemmina G, et al.

Colloids Surf., B 82 , 277-282, (2011)