Galanin-Like Peptide (porcine) trifluoroacetate salt

Galanin-Like Peptide (porcine) trifluoroacetate salt Structure
Galanin-Like Peptide (porcine) trifluoroacetate salt structure
Common Name Galanin-Like Peptide (porcine) trifluoroacetate salt
CAS Number 245114-96-9 Molecular Weight 6204.1
Density N/A Boiling Point N/A
Molecular Formula C281H443N81O78 Melting Point N/A
MSDS USA Flash Point N/A

Galanin modulates the neural niche to favour perineural invasion in head and neck cancer.

Nat. Commun. 6 , 6885, (2015)

Perineural invasion (PNI) is an indicator of poor survival in multiple cancers. Unfortunately, there is no targeted treatment for PNI since the molecular mechanisms are largely unknown. PNI is an active process, suggesting that cancer cells communicate with n...

Galanin-like peptides exert potent vasoactive functions in vivo.

J. Invest. Dermatol. 127(3) , 716-21, (2007)

The cutaneous vasculature plays a key role in the pathophysiology of inflammatory skin diseases. The vascular activity is under the control of the peripheral nervous system that includes locally released neuropeptides. Recently, we detected receptors for the ...

Cloning and distribution of galanin-like peptide mRNA in the hypothalamus and pituitary of the macaque.

Endocrinology 143(3) , 755-63, (2002)

Galanin-like peptide (GALP) is a newly discovered hypothalamic neuropeptide, which is regulated by leptin and implicated in the regulation of GnRH secretion in the rodent. We searched the human genome database and determined that the human GALP gene comprises...

Isolation and cDNA cloning of a novel galanin-like peptide (GALP) from porcine hypothalamus.

J. Biol. Chem. 274(52) , 37041-5, (1999)

Galanin is a widely distributed neuropeptide with a variety of physiological functions. Three galanin receptor subtypes, GALR1, GALR2, and GALR3, have been reported. We isolated a novel galanin-like peptide (GALP) from porcine hypothalamus by observing its ac...

Galanin-like peptide (GALP) mRNA expression is restricted to arcuate nucleus of hypothalamus in adult male rat brain.

Neuroendocrinology 72 , 67, (2000)

Galanin-like peptide (GALP) is a novel 60-amino acid neuropeptide, isolated from porcine hypothalamus and subsequently identified in rats and humans, which has reported selectivity for the Gal-R2 galanin receptor [Ohtaki T et al: J Biol Chem 1999; 274: 37041-...