Avidin

Avidin Structure
Avidin structure
Common Name Avidin
CAS Number 1405-69-2 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS USA Flash Point N/A

YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model.

Oncotarget 6 , 37678-94, (2015)

Ewing sarcoma is an aggressive tumor of bone and soft tissue affecting predominantly children and young adults. Tumor-specific chromosomal translocations create EWS-FLI1 and similar aberrant ETS fusion proteins that drive sarcoma development in patients. ETS ...

A fluorescent "allosteric scorpionand" complex visualizes a biological recognition event.

ChemBioChem. 14(2) , 224-9, (2013)

We describe a new class of fluorescent reporter and its employment to visualize the biotin/avidin binding interaction. Derivatives of the azamacrocycle cyclam that contain a pendant naphthalimide dye are inherently fluorescent when zinc(II) is coordinated. In...

Block copolymer modified surfaces for conjugation of biomacromolecules with control of quantity and activity.

Langmuir 29(4) , 1122-8, (2013)

Polymer brush layers based on block copolymers of poly(oligo(ethylene glycol) methacrylate) (POEGMA) and poly(glycidyl methacrylate) (PGMA) were formed on silicon wafers by activators generated by electron transfer atom transfer radical polymerization (AGET A...

Difference in protein adsorption onto polymer films with or without thermal annealing.

J. Nanosci. Nanotechnol. 14(4) , 3106-11, (2014)

Protein adsorptions onto non-annealed (NA) and thermally annealed (TA) polyetherimide films were examined by surface plasmon resonance measurements. Proteins adsorbed onto the NA films with smaller adsorption constants in comparison with the TA films. Neutron...

Layer by layer assembly of biotinylated protein networks for signal amplification.

Chem. Commun. (Camb.) 49(24) , 2397-9, (2013)

Described herein is a unique and inexpensive method that outperforms commercial methods that amplify the streptavidin-biotin recognition event. Amplification induced by streptavidin and biotinylated protein causes the formation of a large detectable polymer. ...

Nanomechanics of lipid encapsulated microbubbles with functional coatings.

Langmuir 29(12) , 4096-103, (2013)

Microbubbles (MBs) are increasingly being proposed as delivery vehicles for targeted therapeutics, as well as being contrast agents for ultrasound imaging. MBs formed with a lipid shell are promising candidates due to their biocompatibility and the opportunit...

Distinguishing Loss of Structure from Subunit Dissociation for Protein Complexes with Variable Temperature Ion Mobility Mass Spectrometry.

Anal. Chem. 87 , 6271-9, (2015)

The thermal stability and strength of interactions in proteins are commonly measured using isothermal calorimetry and differential scanning calorimetry providing a measurement that averages over structural transitions that occur as the proteins melt and disso...

Supramolecular synergy in the boundary lubrication of synovial joints.

Nat. Commun. 6 , 6497, (2015)

Hyaluronan, lubricin and phospholipids, molecules ubiquitous in synovial joints, such as hips and knees, have separately been invoked as the lubricants responsible for the remarkable lubrication of articular cartilage; but alone, these molecules cannot explai...

A hypersensitive biotin-avidin-TRFIA for quantitative detection of ANA-Ig(GAM) and its clinical application.

J. Immunoassay Immunochem. 34(2) , 197-207, (2013)

We demonstrate herein a novel time-resolved fluoroimmunoassay (TRFIA) with high sensitivity and wide range for quantitative detection of ANA-Ig(GAM) antibodies using a biotin-avidin amplification system. The immunoassay was conducted by following procedures f...

Inherently electroactive graphene oxide nanoplatelets as labels for specific protein-target recognition.

Nanoscale 5(17) , 7844-8, (2013)

Graphene related materials have been widely employed as highly efficient transducers for biorecognition. Here we show a conceptually new approach of using graphene oxide nanoplatelets (50 × 50 nm) as voltammetric inherently active labels for specific protein-...