holo-transferrin
holo-transferrin structure
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Common Name | holo-transferrin | ||
|---|---|---|---|---|
| CAS Number | 11096-37-0 | Molecular Weight | 362.38368 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H22N6O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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LipiD-QuanT: a novel method to quantify lipid accumulation in live cells.
J. Lipid Res. 56 , 2206-16, (2015) Lipid droplets (LDs) are the main storage organelles for triglycerides. Elucidation of lipid accumulation mechanisms and metabolism are essential to understand obesity and associated diseases. Adipogenesis has been well studied in murine 3T3-L1 and human Simp... |
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Differentiation potential of o bombay human-induced pluripotent stem cells and human embryonic stem cells into fetal erythroid-like cells.
Cell J. 16(4) , 426-39, (2015) There is constant difficulty in obtaining adequate supplies of blood components, as well as disappointing performance of "universal" red blood cells. Advances in somatic cell reprogramming of human-induced pluripotent stem cells (hiPSCs) have provided a valua... |
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Streptococcus pneumoniae secretes a glyceraldehyde-3-phosphate dehydrogenase, which binds haemoglobin and haem.
Biometals 27(4) , 683-93, (2014) Streptococcus pneumoniae is a gram positive encapsulated bacterium responsible of septicaemia and upper respiratory infections in children. This pathogen requires iron to survive in the host, which it can obtain of haemoglobin (Hb) or haem. Only two Hb-bindin... |
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Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species.
Endocrinology 156(4) , 1540-51, (2015) Na+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the first and rate-limiting step in the biosynthesis of the thyroid hormones. The expression and function of NIS in thyroid cells is mainly regulated by TSH and by the intracellular conc... |
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Trace fluorescent labeling for protein crystallization.
Acta Crystallogr. F. Struct. Biol. Commun. 71 , 806-14, (2015) Fluorescence can be a powerful tool to aid in the crystallization of proteins. In the trace-labeling approach, the protein is covalently derivatized with a high-quantum-yield visible-wavelength fluorescent probe. The final probe concentration typically labels... |
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Iron for proliferation of cell lines and hematopoietic progenitors: Nailing down the intracellular functional iron concentration.
Biochim. Biophys. Acta 1853 , 1596-605, (2015) Iron is an essential nutrient which must be provided in sufficient amounts to support growth of eukaryotic cells. All organisms devote specialized pathways to ensure proper delivery. Yet, a quantitative assessment of the intra-cellular iron concentration need... |
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Mesenchymal stromal cell proliferation, gene expression and protein production in human platelet-rich plasma-supplemented media.
PLoS ONE 9(8) , e104662, (2014) Platelet-rich plasma (PRP) is increasingly used as a cell culture supplement, in order to reduce the contact of human cells with animal-derived products during in vitro expansion. The effect of supplementation changes on cell growth and protein production is ... |
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Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors.
Blood 127 , 139-48, (2016) Maintaining cellular redox balance is vital for cell survival and tissue homoeostasis because imbalanced production of reactive oxygen species (ROS) may lead to oxidative stress and cell death. The antioxidant enzyme glutathione peroxidase 4 (Gpx4) is a key r... |
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Pyrophosphate-mediated iron acquisition from transferrin in Neisseria meningitidis does not require TonB activity.
PLoS ONE 9(10) , e107612, (2014) The ability to acquire iron from various sources has been demonstrated to be a major determinant in the pathogenesis of Neisseria meningitidis. Outside the cells, iron is bound to transferrin in serum, or to lactoferrin in mucosal secretions. Meningococci can... |
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NF-kappaB mediates mitogen-activated protein kinase pathway-dependent iNOS expression in human melanoma.
J. Invest. Dermatol. 129(1) , 148-54, (2009) Tumor expression of inducible nitric oxide synthase (iNOS) predicts poor outcomes for melanoma patients. We have reported the regulation of melanoma iNOS by the mitogen-activated protein kinase (MAPK) pathway. In this study, we test the hypothesis that NF-kap... |