R-(+)-SKF-81297 hydrobromide
R-(+)-SKF-81297 hydrobromide structure
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Common Name | R-(+)-SKF-81297 hydrobromide | ||
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| CAS Number | 253446-15-0 | Molecular Weight | 370.669 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H17BrClNO2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Inhibition of adult rat retinal ganglion cells by D1-type dopamine receptor activation.
J. Neurosci. 29 , 15001-16, (2009) The spike output of neural pathways can be regulated by modulating output neuron excitability and/or their synaptic inputs. Dopaminergic interneurons synapse onto cells that route signals to mammalian retinal ganglion cells, but it is unknown whether dopamine... |
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The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys.
Eur. J. Pharmacol. 235 , 143, (1993) The alleged selective, high efficacy dopamine D1 receptor agonist, SKF 81297 (0.05-0.3 mg/kg i.m.), induced rotational behaviour away from the lesion and stimulated use of the dominant right hand in unilaterally (left side) 1-methyl-4-phenyl-1,2,3,6-tetrahydr... |
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Pharmacological characterization of the discriminative stimulus properties of the dopamine D1 agonist, SKF 81297.
Behav. Pharmacol. 4 , 135-146, (1993) A range of selective dopamine D1 and D2 receptor agonists and antagonists was used to characterize to the discriminative stimuli produced by d-amphetamine (0.5mg/kg) and the D1 agonists SKF 81297 (0.1mg/kg). In rats trained to discriminate d-amphetamine (0.5m... |
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Differential effects of dopamine D1 and D2 receptor agonists on schedule-controlled behavior of squirrel monkeys.
J. Pharmacol. Exp. Ther. 273 , 40, (1995) The effects of dopamine agonists differing in affinity and selectivity at D1 and D2 types of dopamine receptors were compared in squirrel monkeys responding under two different schedules of reinforcement: a fixed-interval (FI) schedule of stimulus-shock termi... |