Cellulose acetate phthalate

Cellulose acetate phthalate Structure
Cellulose acetate phthalate structure
Common Name Cellulose acetate phthalate
CAS Number 9004-38-0 Molecular Weight 3569.013
Density N/A Boiling Point N/A
Molecular Formula C156H174O95 Melting Point N/A
MSDS Chinese USA Flash Point N/A

Preparation, characterization and dielectric studies on carbonyl iron/cellulose acetate hydrogen phthalate core/shell nanoparticles for drug delivery applications.

Int. J. Pharm. 365(1-2) , 131-5, (2009)

A method to prepare composite colloidal nanoparticles, consisting of a magnetic core (carbonyl iron) and a biodegradable polymeric shell (cellulose acetate hydrogen phthalate) was described and also particle size was characterized by Optical Microscope and Sc...

Sustained-release tablets of indomethacin-loaded microcapsules: preparation, in vitro and in vivo characterization.

Int. J. Pharm. 333(1-2) , 87-94, (2007)

Indomethacin (IDM) was encapsulated in gelatin-cellulose acetate phthalate (CAP) microcapsules (A) by complex coacervation method and in CAP microcapsules (B) by simple coacervation method. Microcapsules A and B, having mean diameters of 38.24 and 35.74 micro...

Restoration of mechanically lengthened jejunum into intestinal continuity in rats.

J. Pediatr. Surg. 46(12) , 2321-6, (2011)

Prior studies demonstrated the feasibility of lengthening intestinal segments with mechanical force, but no previous studies have restored the lengthened segment back into intestinal continuity.A 1-cm segment of isolated rat jejunum was lengthened using a Nit...

Enteric micro-particles for targeted oral drug delivery.

AAPS PharmSciTech 11(4) , 1500-7, (2010)

This work is focused on production of enteric-coated micro-particles for oral administration, using a water-in-oil-in-water solvent evaporation technique. The active agent theophylline was first encapsulated in cellulose acetate phthalate (CAP), a pH-sensitiv...

Bioactivity of WLBU2 peptide antibiotic in combination with bioerodible polymer.

Int. J. Antimicrob. Agents 38(6) , 530-3, (2011)

WLBU2 is a peptide antibiotic designed for broad antimicrobial activity, including bacteria associated with periodontal disease. Although periodontitis is associated with various systemic conditions, ranging from cardiovascular disease to preterm birth, local...

Preparation and characterization of biodegradable urea-loaded microparticles as an approach for transdermal delivery.

J. Microencapsul. 23(6) , 698-712, (2006)

This work describes the formulation and characterization of urea-loaded microspheres prepared using various polymers such as ethyl cellulose (EC), cellulose acetate phthalate (CAP) and poly (D,L-lactic-co-glycolic acid) (PLGA), along with the utilization of a...

Effects of composition and setting environment on mechanical properties of a composite bone filler.

J. Biomed. Mater. Res. A 101(4) , 973-80, (2013)

Large bone defects can be difficult to treat, even with autografts. Bone graft substitutes, such as calcium sulfate (CS), calcium phosphate cements, and hydroxyapatite, are receiving significant attention because of their biocompatibility and potential for in...

Development of a gel permeation chromatographic assay to achieve mass balance in cellulose acetate phthalate stability studies

J. Pharm. Biomed. Anal. 49(2) , 240-6, (2009)

Cellulose acetate phthalate (CAP, cellulose acetate 1,2-benzenedicarboxylate) is a common polymeric oral tablet coating. CAP is also a vaginal microbicide candidate that potently inhibits HIV-1 proliferation. This paper describes the development of a precise,...

Eudragit-S, Eudragit-L and cellulose acetate phthalate coated polysaccharide tablets for colonic targeted delivery of azathioprine.

Pharm. Dev. Technol. 15(4) , 431-7, (2010)

The present work deals with the formulation and evaluation of polymer-coated polysaccharide tablets of azathioprine prepared by direct compression method using different ratios of avicel (MCC), inulin and triacetin. The tablets formulations containing 25 mg o...

Controlled release polymeric ocular delivery of acyclovir.

Pharm. Dev. Technol. 15(4) , 369-78, (2010)

The aim of the present study was to formulate and evaluate controlled release polymeric ocular delivery of acyclovir. Reservoir-type ocular inserts were fabricated by sandwiching hydroxypropyl methylcellulose (HPMC) matrix film containing acyclovir between tw...