1-Oleoyl-2-palmitoyl-sn-glycero-3-PC

1-Oleoyl-2-palmitoyl-sn-glycero-3-PC Structure
1-Oleoyl-2-palmitoyl-sn-glycero-3-PC structure
Common Name 1-Oleoyl-2-palmitoyl-sn-glycero-3-PC
CAS Number 59491-62-2 Molecular Weight 760.076
Density N/A Boiling Point N/A
Molecular Formula C42H82NO8P Melting Point N/A
MSDS USA Flash Point N/A

Barotropic and thermotropic bilayer phase behavior of positional isomers of unsaturated mixed-chain phosphatidylcholines.

Biochim. Biophys. Acta 1788(5) , 1056-63, (2009)

The bilayer phase transitions of six kinds of mixed-chain phosphatidylcholines (PCs) with an unsaturated acyl chain in the sn-1 or sn-2 position, 1-oleoyl-2-stearoyl- (OSPC), 1-stearoyl-2-oleoyl- (SOPC), 1-oleoyl-2-palmitoyl- (OPPC), 1-palmitoyl-2-oleoyl- (PO...

Bridging the gap between molecular descriptors and mechanism: Cases studies by molecular dynamics simulations

J. Mol. Graph. Model. 27(7) , 829-35, (2009)

In recent years, both classification models and quantitative structure–activity relationships (QSARs) have been developed to discriminate the acute toxicity of polar narcotics and uncouplers. One of fundamental issues is how to select and interpret the molecu...

The cytoplasmic region of mouse Fc gamma RIIb1, but not Fc gamma RIIb2, binds phospholipid membranes.

Biochemistry 38(7) , 2102-9, (1999)

The cytoplasmic regions of the mouse low-affinity Fc gamma RII isoforms, Fc gamma RIIb1 and Fc gamma RIIb2, play key roles in signal transduction by mediating different cellular functions. The Fc gamma RIIb1 (94 residues) and Fc gamma RIIb2 (47 residues) cyto...

Immobilized liposome chromatography for studies of protein-membrane interactions and refolding of denatured bovine carbonic anhydrase.

J. Chromatogr. B. Biomed. Sci. Appl. 712(1-2) , 59-71, (1998)

Small unilamellar vesicles (SUVs) composed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine and 1 mol% phosphatidylethanolamine were covalently coupled to chromatographic gel beads. Interactions of liposomal lipid bilayers with several water-soluble protei...

ETC-588 (Pfizer).

Curr. Opin. Investig. Drugs 5(9) , 993-9, (2004)

Pfizer, following its acquisition of Esperion Therapeutics in the first quarter of 2004, is developing ETC-588 as a potential acute treatment for ischemia caused by atherosclerosis. Enrollment in phase II trials in patients with acute coronary syndrome is com...

Fourier transform infrared spectroscopy as a probe for the study of the hydration of lipid self-assemblies. I. Methodology and general phenomena.

Biospectroscopy 4(4) , 267-80, (1998)

An algorithm for the study of the gradual hydration of phospholipid assemblies by means of Fourier transform infrared (FTIR) spectroscopy is presented. A complete series of diacyl phosphatidylcholines (PCs) including all possible analogues with palmitoyl and ...

Immobilization reduces the activity of surface-bound cationic antimicrobial peptides with no influence upon the activity spectrum.

Antimicrob. Agents Chemother. 53(3) , 1132-41, (2009)

Early studies of immobilized peptides mainly focused upon the relationship between structural properties and the activity of soluble and surface-tethered sequences. The intention of this study was to analyze the influence of immobilization parameters upon the...

Thermal and 13C-NMR study of the dynamic structure of 1-palmitoyl-2-oleyl-sn-glycero-3-phosphocholine and 1-oleyl-2-palmitoyl-sn-glycero-3-phosphocholine in aqueous dispersions.

Biochim. Biophys. Acta 687(2) , 231-7, (1982)

Mixed-acid monounsaturated phosphatidylcholines containing palmitate and oleate chains have been synthesized by phospholipase A2 digestion of the appropriate single-acid phosphatidylcholine, followed by reacylation of the lysophosphatidylcholine with the desi...

A new mechanism for ozonolysis of unsaturated organics on solids: phosphocholines on NaCl as a model for sea salt particles.

Phys. Chem. Chem. Phys. 10(4) , 528-41, (2008)

The ozonolysis of an approximately one monolayer film of 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine (OPPC) on NaCl was followed in real time using diffuse reflection infrared Fourier transform spectrometry (DRIFTS) at 23 degrees C. Matrix-assisted laser...

Heat-enhanced production of chitosanase from Streptomyces griseus in the presence of liposome.

J. Biosci. Bioeng. 100(5) , 495-501, (2005)

The effects of heat stress and liposome treatment on the growth of Streptomyces griseus cells and chitosanase production were investigated on the basis of using the designed strategy of a stress-mediated bioprocess. The effective conditions for increasing the...