Micrococcal nuclease
Micrococcal nuclease structure
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Common Name | Micrococcal nuclease | ||
|---|---|---|---|---|
| CAS Number | 9013-53-0 | Molecular Weight | 295.29 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H22N4O7S2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells.
Genes Dev. 29 , 1298-315, (2015) Mutant p53 impacts the expression of numerous genes at the level of transcription to mediate oncogenesis. We identified vascular endothelial growth factor receptor 2 (VEGFR2), the primary functional VEGF receptor that mediates endothelial cell vascularization... |
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E2F1-mediated FOS induction in arsenic trioxide-induced cellular transformation: effects of global H3K9 hypoacetylation and promoter-specific hyperacetylation in vitro.
Environ. Health Perspect. 123 , 484-92, (2015) Aberrant histone acetylation has been observed in carcinogenesis and cellular transformation associated with arsenic exposure; however, the molecular mechanisms and cellular outcomes of such changes are poorly understood.We investigated the impact of tolerate... |
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Genome-wide in vitro reconstitution of yeast chromatin with in vivo-like nucleosome positioning.
Meth. Enzymol. 513 , 205-32, (2012) Recent genome-wide mapping of nucleosome positions revealed that well-positioned nucleosomes are pervasive across eukaryotic genomes, especially in important regulatory regions such as promoters or origins of replication. As nucleosomes impede access to DNA, ... |
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A rapid, high-throughput screening method for carriage of methicillin-resistant Staphylococcus aureus.
APMIS 121(9) , 865-70, (2013) Rapid screening of methicillin-resistant Staphylococcus aureus (MRSA) colonization prior to hospital admittance is important to reduce nosocomial infections and health care costs. Molecular detection of mecA and S. aureus specific target genes has become wide... |
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Characterization and comparative analysis of a second thermonuclease from Staphylococcus aureus.
Microbiol. Res. 168(3) , 174-82, (2013) Staphylococcal nuclease (here termed as Nuc1) is considered an important virulence factor and a unique marker widely used in the detection of Staphylococcus aureus. A second functional thermostable nuclease (here termed as Nuc2) in S. aureus was characterized... |
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Telomeric repeats act as nucleosome-disfavouring sequences in vivo.
Nucleic Acids Res. 42(3) , 1541-52, (2014) Telomeric DNAs consist of tandem repeats of G-clusters such as TTAGGG and TG1-3, which are the human and yeast repeat sequences, respectively. In the yeast Saccharomyces cerevisiae, the telomeric repeats are non-nucleosomal, whereas in humans, they are organi... |
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Local tertiary structure probing of ribonucleoprotein particles by nuclease fusion proteins.
PLoS ONE 7(8) , e42449, (2012) Analyses of the conformational dynamics of the numerous cellular ribonucleoprotein particles (RNP) significantly contribute to the understanding of their modes of action. Here, we tested whether ribonuclease fusion proteins incorporated into RNPs can be used ... |
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Characterization of adhesin genes, staphylococcal nuclease, hemolysis, and biofilm formation among Staphylococcus aureus strains isolated from different sources.
Foodborne Pathog. Dis. 10(9) , 757-63, (2013) Staphylococcus aureus is a pathogenic bacterium capable of developing biofilms, leading to nosocomial infection and cross-contamination of foods. The current study was focused on the detection of adhesin genes, staphylococcal nuclease and hemolytic activities... |
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Comparison of the Isw1a, Isw1b, and Isw2 nucleosome disrupting activities.
Biochemistry 52(40) , 6940-9, (2013) The three Saccharomyces cerevisiae ISWI chromatin remodeling complexes, Isw1a, Isw1b, and Isw2, are implicated in the regularization of arrayed nucleosomes and regulation of gene activity. Although Isw1a and Isw1b are based on the same catalytic unit, in gene... |
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Structural and thermodynamic insights into the recognition of native proteins by anti-peptide antibodies.
J. Mol. Biol. 425(11) , 2027-38, (2013) Perlecan is a major heparan sulfate (HS) proteoglycan in the arterial wall. Previous studies have linked it to atherosclerosis. Perlecan contains a core protein and three HS side chains. Its core protein has five domains (DI-DV) with disparate structures and ... |