boc-achpa

boc-achpa Structure
boc-achpa structure
Common Name boc-achpa
CAS Number 98105-45-4 Molecular Weight 315.40500
Density 1.121 g/cm3 Boiling Point 498.1ºC at 760 mmHg
Molecular Formula C16H29NO5 Melting Point N/A
MSDS Chinese USA Flash Point 255ºC

Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine.

J. Med. Chem. 28(12) , 1779-90, (1985)

Analogues of the renin octapeptide substrate were synthesized in which replacement of the scissile dipeptide with (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid (statine, Sta) transformed the substrate sequence into potent, transition-state analogue, compet...