![]() 1,3-Diphenylurea structure
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Common Name | 1,3-Diphenylurea | ||
---|---|---|---|---|
CAS Number | 102-07-8 | Molecular Weight | 212.25 | |
Density | 1.1±0.1 g/cm3 | Boiling Point | 374.6±25.0 °C at 760 mmHg | |
Molecular Formula | C13H12N2O | Melting Point | 239-241 °C(lit.) | |
MSDS | USA | Flash Point | 180.4±23.2 °C |
The structure-activity relationship of urea derivatives as anti-tuberculosis agents.
Bioorg. Med. Chem. 19 , 5585-95, (2011) The treatment of tuberculosis is becoming more difficult due to the ever increasing prevalence of drug resistance. Thus, it is imperative that novel anti-tuberculosis agents, with unique mechanisms of action, be discovered and developed. The direct anti-tuber... |
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Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps.
Eur. J. Med. Chem. 43 , 2453-63, (2008) Bacterial efflux pump systems contribute to antimicrobial resistance in pathogenic bacteria. The co-administration of bacterial efflux pump inhibitors with antibiotics is being pursued to overcome efflux-mediated resistance to antibiotics. In this study we in... |
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Selectivity of kinase inhibitor fragments.
J. Med. Chem. 54 , 5131-43, (2011) A kinase-focused screening set of fragments has been assembled and has proved successful for the discovery of ligand-efficient hits against many targets. Here we present some of our general conclusions from this exercise. Notably, we present the first profili... |
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Dispersive liquid-liquid microextraction for the determination of three cytokinin compounds in fruits and vegetables by liquid chromatography with time-of-flight mass spectrometry.
Talanta 116 , 376-81, (2013) The paper presents a novel approach for the determination of three cytokinin compounds, thidiazuron (TDZ), 1,3-diphenylurea (1,3-DPU) and forchlorfenuron (CPPU), in fruit and vegetables samples using liquid chromatography with electrospray ionization and time... |
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Metabolism of diphenylurea by a Marinobacter sp. isolated from a contaminated ephemeral stream bed in the Negev Desert.
FEMS Microbiol. Lett. 213(2) , 199-204, (2002) A moderate halophilic Marinobacter sp. (designated strain DPUZ) able to metabolize 1,3-diphenylurea (DPU) was isolated from a contaminated ephemeral desert stream bed near an industrial complex in the northern part of the Negev Desert (Israel). Metabolism of ... |
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