Somatotropin
Somatotropin structure
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Common Name | Somatotropin | ||
|---|---|---|---|---|
| CAS Number | 12629-01-5 | Molecular Weight | 22124.12 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1580.5±75.0 °C at 760 mmHg | |
| Molecular Formula | C990H1529N263O299S7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 909.7±37.1 °C | |
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Pattern of IGF-1 variants' expression in human cancer cell lines using a novel q-RT-PCR approach.
Anticancer Res. 35(1) , 107-15, (2015) Although insulin-like growth factor-1 (IGF-1) is well-implicated in cancer biology, the potential roles of IGF-1 variants in different types of cancer are largely unknown. The aim of the present study was to in vitro characterize several human cancers for the... |
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Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells.
Hepatology 60(2) , 700-14, (2014) Cholangiocytes are biliary epithelial cells, which, like hepatocytes, originate from hepatoblasts during embryonic development. In this study we investigated the potential of human embryonic stem cells (hESCs) to differentiate into cholangiocytes and we repor... |
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Management of endocrine disease: clinicopathological classification and molecular markers of pituitary tumours for personalized therapeutic strategies.
Eur. J. Endocrinol. 170(4) , R121-32, (2014) Pituitary tumours, the most frequent intracranial tumour, are historically considered benign. However, various pieces of clinical evidence and recent advances in pathological and molecular analyses suggest the need to consider these tumours as more than an en... |
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Effect of long-term GH replacement therapy on cardiovascular outcomes in isolated GH deficiency compared with multiple pituitary hormone deficiencies: a sub-analysis from the Dutch National Registry of Growth Hormone Treatment in Adults.
Eur. J. Endocrinol. 171(2) , 151-60, (2014) Isolated GH deficiency (IGHD) could provide a model to investigate the influence of GH deficiency per se and the effect of GH replacement therapy without the influence from other pituitary hormone deficiencies or their treatment. The aim of this study is to a... |
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Developing interventions for cancer-related cognitive dysfunction in childhood cancer survivors.
J. Natl. Cancer Inst. 106(8) , doi:10.1093/jnci/dju186, (2014) Survivors of childhood cancer frequently experience cancer-related cognitive dysfunction, commonly months to years after treatment for pediatric brain tumors, acute lymphoblastic leukemia (ALL), or tumors involving the head and neck. Risk factors for cancer-r... |
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Gender differences in GH response to GHRH+ARG in lipodystrophic patients with HIV: a key role for body fat distribution.
Eur. J. Endocrinol. 170(5) , 685-96, (2014) Gender influence on GH secretion in human immunodeficiency virus (HIV)-infected patients is poorly known.To determine the effect of gender, we compared GH response to GH-releasing hormone plus arginine (GHRH+Arg), and body composition in 103 men and 97 women ... |
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[Endocrine abnormalities in a patient with borderline personality disorder--case 8/2014].
Dtsch. Med. Wochenschr. 139(50) , 2602, (2014) We report on a 44-year-old woman who was treated for borderline personality disorder in the Department of Psychiatry. In addition, symptoms of hyperthyroidism (anxiety, weight loss, hyperdefecation) were noticeable. Thyroid stimulating hormone (TSH) was margi... |
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A critical evaluation of bioimpedance spectroscopy analysis in estimating body composition during GH treatment: comparison with bromide dilution and dual X-ray absorptiometry.
Eur. J. Endocrinol. 172(1) , 21-8, (2015) To compare estimates by bioimpedance spectroscopy analysis (BIS) of extracellular water (ECW), fat mass (FM), and fat-free mass (FFM) against standard techniques of bromide dilution and dual energy X-ray absorptiometry (DXA) during intervention that causes si... |
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GH administration rescues fatty liver regeneration impairment by restoring GH/EGFR pathway deficiency.
Endocrinology 155(7) , 2545-54, (2014) GH pathway has been shown to play a major role in liver regeneration through the control of epidermal growth factor receptor (EGFR) activation. This pathway is down-regulated in nonalcoholic fatty liver disease. Because regeneration is known to be impaired in... |
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Hormonal responses of combining endurance-resistance exercise in healthy young men.
J. Sports Med. Phys. Fitness 54(2) , 244-51, (2014) This study investigated the influence of resistance (R) following endurance (E) exercise or ER on acute hormonal responses, such as growth hormone (GH), total testosterone (TT), free testosterone (FT), IGF-1, and cortisol.Ten healthy young men with an average... |