Fibroblast Growthfactor, Basic
Fibroblast Growthfactor, Basic structure
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Common Name | Fibroblast Growthfactor, Basic | ||
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| CAS Number | 106096-93-9 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Thermogenic activity of UCP1 in human white fat-derived beige adipocytes.
Mol. Endocrinol. 29(1) , 130-9, (2014) Heat-producing beige/brite (brown-in-white) adipocytes in white adipose tissue have the potential to suppress metabolic disease in mice and hold great promise for the treatment of obesity and type 2 diabetes in humans. Here, we demonstrate that human adipose-... |
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A re-assessment of long distance growth and connectivity of neural stem cells after severe spinal cord injury.
Exp. Neurol. 257 , 186-204, (2014) As part of the NIH "Facilities of Research Excellence-Spinal Cord Injury" project to support independent replication, we repeated key parts of a study reporting robust engraftment of neural stem cells (NSCs) treated with growth factors after complete spinal c... |
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A novel role for FGF and extracellular signal-regulated kinase in gap junction-mediated intercellular communication in the lens.
J. Cell Biol. 154 , 197-216, (2001) Gap junction-mediated intercellular coupling is higher in the equatorial region of the lens than at either pole, a property believed to be essential for lens transparency. We show that fibroblast growth factor (FGF) upregulates gap junctional intercellular dy... |
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Differentiation of Wharton's jelly mesenchymal stem cells into neurons in alginate scaffold.
Neural Regen. Res. 10 , 1312-6, (2015) Alginate scaffold has been considered as an appropriate biomaterial for promoting the differentiation of embryonic stem cells toward neuronal cell lineage. We hypothesized that alginate scaffold is suitable for culturing Wharton's jelly mesenchymal stem cells... |
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Osteogenic differentiation of human mesenchymal stem cells in the absence of osteogenic supplements: A surface-roughness gradient study.
Acta Biomater. 28 , 64-75, (2015) The use of biomaterials to direct osteogenic differentiation of human mesenchymal stem cells (hMSCs) in the absence of osteogenic supplements is thought to be part of the next generation of orthopedic implants. We previously engineered surface-roughness gradi... |
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Characterization of ectopic colonies that form in widespread areas of the nervous system with neural stem cell transplants into the site of a severe spinal cord injury.
J. Neurosci. 34(42) , 14013-21, (2014) We reported previously the formation of ectopic colonies in widespread areas of the nervous system after transplantation of fetal neural stem cells (NSCs) into spinal cord transection sites. Here, we characterize the incidence, distribution, and cellular comp... |
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Combination treatment with ethyl pyruvate and IGF-I exerts neuroprotective effects against brain injury in a rat model of neonatal hypoxic-ischemic encephalopathy.
Int. J. Mol. Med. 36 , 195-203, (2015) Neonatal hypoxic-ischemic (HI) brain injury causes severe brain damage in newborns. Following HI injury, rapidly accumulating oxidants injure neurons and interrupt ongoing developmental processes. The antioxidant, sodium pyruvate, has been shown to reduce neu... |
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Human melanocytes mitigate keratinocyte-dependent contraction in an in vitro collagen contraction assay.
Burns 41 , 1035-42, (2015) Scarring is an extensive problem in burn care, and treatment can be especially complicated in cases of hypertrophic scarring. Contraction is an important factor in scarring but the contribution of different cell types remains unclear. We have investigated the... |
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Epimorphic regeneration approach to tissue replacement in adult mammals.
Proc. Natl. Acad. Sci. U. S. A. 107 , 3351-5, (2010) Urodeles and fetal mammals are capable of impressive epimorphic regeneration in a variety of tissues, whereas the typical default response to injury in adult mammals consists of inflammation and scar tissue formation. One component of epimorphic regeneration ... |
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Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells.
Nat. Cell Biol. 18 , 418-30, (2016) Aberrant Notch signalling has been linked to many cancers including choroid plexus (CP) tumours, a group of rare and predominantly paediatric brain neoplasms. We developed animal models of CP tumours, by inducing sustained expression of Notch1, that recapitul... |