Carnitine Acetyltransferase from pigeon breast muscle
Carnitine Acetyltransferase from pigeon breast muscle structure
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Common Name | Carnitine Acetyltransferase from pigeon breast muscle | ||
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| CAS Number | 9029-90-7 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res. 14 , 2121-7, (2004) The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for every human and mouse gene. The project initially used a r... |
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Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Science 325(5942) , 834-40, (2009) Lysine acetylation is a reversible posttranslational modification of proteins and plays a key role in regulating gene expression. Technological limitations have so far prevented a global analysis of lysine acetylation's cellular roles. We used high-resolution... |
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DNA sequence and analysis of human chromosome 9.
Nature 429(6990) , 369-74, (2004) Chromosome 9 is highly structurally polymorphic. It contains the largest autosomal block of heterochromatin, which is heteromorphic in 6-8% of humans, whereas pericentric inversions occur in more than 1% of the population. The finished euchromatic sequence of... |
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Role of carnitine acetyltransferases in acetyl coenzyme A metabolism in Aspergillus nidulans.
Eukaryotic Cell 10 , 547-555, (2011) The flow of carbon metabolites between cellular compartments is an essential feature of fungal metabolism. During growth on ethanol, acetate, or fatty acids, acetyl units must enter the mitochondrion for metabolism via the tricarboxylic acid cycle, and acetyl... |
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PPAR-γ regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow.
PLoS ONE 7(9) , e41555, (2012) Carnitine homeostasis is disrupted in lambs with endothelial dysfunction secondary to increased pulmonary blood flow (Shunt). Our recent studies have also indicated that the disruption in carnitine homeostasis correlates with a decrease in PPAR-γ expression i... |
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Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility.
Cell Metab. 15(5) , 764-77, (2012) The concept of "metabolic inflexibility" was first introduced to describe the failure of insulin-resistant human subjects to appropriately adjust mitochondrial fuel selection in response to nutritional cues. This phenomenon has since gained increasing recogni... |
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The cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study.
Circ. Cardiovasc. Imaging 5(2) , 201-9, (2012) Carnitine acetyltransferase catalyzes the reversible conversion of acetyl-coenzyme A (CoA) into acetylcarnitine. The aim of this study was to use the metabolic tracer hyperpolarized [2-(13)C]pyruvate with magnetic resonance spectroscopy to determine whether c... |
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Contributions of carnitine acetyltransferases to intracellular acetyl unit transport in Candida albicans.
J. Biol. Chem. 285(32) , 24335-46, (2010) Transport of acetyl-CoA between intracellular compartments is mediated by carnitine acetyltransferases (Cats) that reversibly link acetyl units to the carrier molecule carnitine. The genome of the opportunistic pathogenic yeast Candida albicans encodes severa... |
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Metabolomic analysis reveals that carnitines are key regulatory metabolites in phase transition of the locusts.
Proc. Natl. Acad. Sci. U. S. A. 109(9) , 3259-63, (2012) Phenotypic plasticity occurs prevalently and plays a vital role in adaptive evolution. However, the underlying molecular mechanisms responsible for the expression of alternate phenotypes remain unknown. Here, a density-dependent phase polyphenism of Locusta m... |
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Altered carnitine homeostasis is associated with decreased mitochondrial function and altered nitric oxide signaling in lambs with pulmonary hypertension.
Am. J. Physiol. Lung Cell. Mol. Physiol. 294(1) , L46-56, (2008) Utilizing aortopulmonary vascular graft placement in the fetal lamb, we have developed a model (shunt) of pulmonary hypertension that mimics congenital heart disease with increased pulmonary blood flow. Our previous studies have identified a progressive devel... |