γ-Glutamyl hydrolase
γ-Glutamyl hydrolase structure
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Common Name | γ-Glutamyl hydrolase | ||
|---|---|---|---|---|
| CAS Number | 9074-87-7 | Molecular Weight | 495.312 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 621.8±65.0 °C at 760 mmHg | |
| Molecular Formula | C21H14BrF3N2O2S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 329.9±34.3 °C | |
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Purification and properties of carboxypeptidase G 1 .
J. Biol. Chem. 246(23) , 7207-13, (1971)
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Headache: new genes, new mechanisms, and new therapies.
Lancet Neurol. 10(1) , 13-4, (2011)
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Clearing up the confusion over the glutamate carboxypeptidase II gene.
Am. J. Med. Genet. A 130A(3) , 327; author reply 329-30, (2004)
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Gene polymorphisms of folate metabolizing enzymes and the risk of gastric cancer.
Cancer Lett. 251(2) , 228-36, (2007) Multiple studies have reported an association between disturbances of folate metabolism and increased risk of gastric cancer, including low intake of folate, low levels of folate in blood or genetic factors affecting folate metabolism. Among the genetic facto... |
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Glutamate carboxypeptidase activity in human skin biopsies as a pharmacodynamic marker for clinical studies.
J. Transl. Med. 9 , 27, (2011) Glutamate excitotoxicity is thought to be involved in the pathogenesis of neurodegenerative disease. One potential source of glutamate is N-acetyl-aspartyl-glutamate (NAAG) which is hydrolyzed to glutamate and N-acetyl-aspartate (NAA) in a reaction catalyzed ... |
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Role of parental folate pathway single nucleotide polymorphisms in altering the susceptibility to neural tube defects in South India.
J. Perinat. Med. 38(1) , 63-9, (2010) To investigate the role of four parental folate pathway single nucleotide polymorphisms (SNPs) i.e., methylene tetrahydrofolate reductase (MTHFR) 677C>T, MTHFR 1298A>C, methionine synthase reductase (MTRR) 66A>G and glutamate carboxypeptidase (GCP) II 1561C>T... |
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ALTERED MERISTEM PROGRAM 1 is involved in development of seed dormancy in Arabidopsis.
PLoS ONE 6(5) , e20408, (2011) Mutants in the rice PLASTOCHRON 3 and maize VIVIPAROUS 8 genes have been shown to have reduced dormancy and ABA levels. In this study we used several mutants in the orthologous gene ALTERED MERISTEM PROGRAM 1 (AMP1) to determine its role in seed dormancy in A... |
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TRICOT encodes an AMP1-related carboxypeptidase that regulates root nodule development and shoot apical meristem maintenance in Lotus japonicus.
Development 140(2) , 353-61, (2013) During the course of evolution, mainly leguminous plants have acquired the ability to form de novo structures called root nodules. Recent studies on the autoregulation and hormonal controls of nodulation have identified key mechanisms and also indicated a pos... |
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The evolutionarily conserved TOUGH protein is required for proper development of Arabidopsis thaliana.
Plant Cell 17(9) , 2473-85, (2005) In this study, we characterize the evolutionarily conserved TOUGH (TGH) protein as a novel regulator required for Arabidopsis thaliana development. We initially identified TGH as a yeast two-hybrid system interactor of the transcription initiation factor TATA... |
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Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III.
FEBS J. 276(16) , 4448-62, (2009) Glutamate carboxypeptidase III (GCPIII) is a metalloenzyme that belongs to the transferrin receptor/glutamate carboxypeptidase II (GCPII; EC 3.4.17.21) superfamily. GCPIII has been studied mainly because of its evolutionary relationship to GCPII, an enzyme in... |