Phosphogluconate dehydrogenase (NADP, decarboxylating)
Phosphogluconate dehydrogenase (NADP, decarboxylating) structure
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Common Name | Phosphogluconate dehydrogenase (NADP, decarboxylating) | ||
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| CAS Number | 9073-95-4 | Molecular Weight | 495.312 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 621.8±65.0 °C at 760 mmHg | |
| Molecular Formula | C21H14BrF3N2O2S | Melting Point | N/A | |
| MSDS | USA | Flash Point | 329.9±34.3 °C | |
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Initial characterization of the human central proteome.
BMC Syst. Biol. 5 , 17, (2011) On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitously expressed in all human cells. Composition and properties... |
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Complete sequencing and characterization of 21,243 full-length human cDNAs.
Nat. Genet. 36 , 40-5, (2004) As a base for human transcriptome and functional genomics, we created the "full-length long Japan" (FLJ) collection of sequenced human cDNAs. We determined the entire sequence of 21,243 selected clones and found that 14,490 cDNAs (10,897 clusters) were unique... |
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res. 14 , 2121-7, (2004) The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for every human and mouse gene. The project initially used a r... |
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Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Science 325(5942) , 834-40, (2009) Lysine acetylation is a reversible posttranslational modification of proteins and plays a key role in regulating gene expression. Technological limitations have so far prevented a global analysis of lysine acetylation's cellular roles. We used high-resolution... |
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The DNA sequence and biological annotation of human chromosome 1.
Nature 441 , 315-321, (2006) The reference sequence for each human chromosome provides the framework for understanding genome function, variation and evolution. Here we report the finished sequence and biological annotation of human chromosome 1. Chromosome 1 is gene-dense, with 3,141 ge... |
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Involvement of the oxidative pentose phosphate pathway in thiamine biosynthesis in Salmonella typhimurium.
J. Bacteriol. 178(5) , 1476-9, (1996) purF mutants of Salmonella typhimurium are known to require a source of both purine and thiamine; however, exogenous pantothenate may be substituted for the thiamine requirement. We show here that the effect of pantothenate is prevented by blocks in the oxida... |
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Limiting role of 6-phosphogluconolactonase in erythrocyte hexose monophosphate pathway metabolism.
J. Lab. Clin. Med. 106(5) , 573-7, (1985) The natural product of the glucose-6-phosphate dehydrogenase reaction is 6-phosphoglucono-delta-lactone, which must be hydrolyzed to 6-phosphogluconic acid before it can be further metabolized by 6-phosphogluconate dehydrogenase. Because this lactone is very ... |
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Kinetic studies of Haemophilus influenzae 6-phosphogluconate dehydrogenase.
Biochim. Biophys. Acta 994(1) , 75-80, (1989) Haemophilus influenzae 6-phosphogluconate dehydrogenase (6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating), EC 1.1.1.44) was purified 308-fold to electrophoretic homogeneity with a 16% recovery through a five-step procedure involving salt fractio... |
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Hexose-6-phosphate and 6-phosphogluconate dehydrogenases of rat liver microsomes. Involvement in NADPH and carbon dioxide generation in the luminal space of microsomal vesicles.
J. Biochem. 92(2) , 547-57, (1982) Rat liver microsomal fraction generates 14CO2 from [1(-14)C]glucose 6-phosphate in the presence of NADP+ and a detergent. The activity is mediated through an enzyme system consisting of hexose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase inh... |
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Identification of a cDNA encoding 6-phosphogluconate dehydrogenase from a human heart cDNA library.
Biochem. Genet. 34(9-10) , 367-73, (1996) A full-length cDNA clone for human 6-phosphogluconate dehydrogenase (PGD) was isolated from a human adult heart cDNA library. The clone encoded an open reading frame of 483 amino acids. When the amino acid sequences of human PGD and sheep PGD were aligned, 94... |