2-piperidin-1-ylethyl 4-amino-5-chloro-2-methoxybenzoate
2-piperidin-1-ylethyl 4-amino-5-chloro-2-methoxybenzoate structure
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Common Name | 2-piperidin-1-ylethyl 4-amino-5-chloro-2-methoxybenzoate | ||
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| CAS Number | 148868-55-7 | Molecular Weight | 312.79200 | |
| Density | 1.223g/cm3 | Boiling Point | 472.7ºC at 760 mmHg | |
| Molecular Formula | C15H21ClN2O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 239.7ºC | |
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Design and synthesis of specific probes for human 5-HT4 receptor dimerization studies.
J. Med. Chem. 48 , 6220-6228, (2005) Recently, human 5-HT4 receptors have been demonstrated to form constitutive dimers in living cells. To evaluate the role of dimerization on the 5-HT4 receptor function, we investigated the conception and the synthesis of bivalent molecules able to influence t... |
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New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors.
J. Med. Chem. 40 , 608-621, (1997) A number of benzoates derived from 4-amino-5-chloro-2-methoxybenzoic acid and substituted 1-piperidineethanol were synthesized and found to be potent 5-HT4 receptor agonists in the electrically-stimulated myenteric plexus and longitudinal muscle of the guinea... |
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Intestinal motor stimulation by the 5-HT4 receptor agonist ML10302: differential involvement of tachykininergic pathways in the canine small bowel and colon.
Neurogastroenterol. Motil. 13 , 543-553, (2001) 5-Hydroxytryptamine (5-HT)4 receptor agonists stimulate gut motility through cholinergic pathways, although there are data suggesting that noncholinergic (tachykininergic) excitatory pathways may also be involved. Differences may exist between the small bowel... |