PEPA
PEPA structure
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Common Name | PEPA | ||
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| CAS Number | 141286-78-4 | Molecular Weight | 402.43600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H16F2N2O4S2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Positive modulation of AMPA receptors prevents downregulation of GluR2 expression and activates the Lyn-ERK1/2-CREB signaling in rat brain ischemia.
Psychopharmacology 20 , 65-77, (2010) alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) are responsible for excitotoxicity induced by ischemic injury in hippocampal CA1 neurons, whereas the molecular mechanisms responsible for their neurotrophic activities are much less ... |
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Activation of AMPA receptor in the infralimbic cortex facilitates extinction and attenuates the heroin-seeking behavior in rats.
Neurosci. Lett. 612 , 126-31, (2016) Infralimbic cortex (IL) is proposed to suppress cocaine seeking after extinction, but whether the IL regulates the extinction and reinstatement of heroin-seeking behavior is unknown. To address this issue, the male SD rats were trained to self-administer hero... |
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The rostromedial tegmental nucleus modulates behavioral inhibition following cocaine self-administration in rats.
Neuropsychopharmacology 40(4) , 861-73, (2015) Recent findings suggest that the mesolimbic dopamine neurons, known to promote cocaine-seeking behavior, are strongly inhibited by a newly characterized region of the midbrain known as the rostromedial tegmental nucleus (RMTg). The RMTg appears to be involved... |