Fusicoccin-A
Fusicoccin-A structure
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Common Name | Fusicoccin-A | ||
|---|---|---|---|---|
| CAS Number | 20108-30-9 | Molecular Weight | 680.823 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 760.2±60.0 °C at 760 mmHg | |
| Molecular Formula | C36H56O12 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 227.0±26.4 °C | |
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Identification and characterisation of the phenolics of Ilex glabra L. Gray (Aquifoliaceae) leaves by liquid chromatography tandem mass spectrometry.
Plant Physiol. Biochem. 70 , 504-11, (2013) The phenolics of the leaves of Ilex glabra L. Gray (Aquifoliaceae) were investigated qualitatively by LC-MS(n). Thirty-two phenolics were detected and characterised on the basis of their unique fragmentation pattern in the negative ion mode tandem MS spectra.... |
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Apoplastic alkalinization is instrumental for the inhibition of cell elongation in the Arabidopsis root by the ethylene precursor 1-aminocyclopropane-1-carboxylic acid.
Plant Physiol. 155(4) , 2049-55, (2011) In Arabidopsis (Arabidopsis thaliana; Columbia-0) roots, the so-called zone of cell elongation comprises two clearly different domains: the transition zone, a postmeristematic region (approximately 200-450 μm proximal of the root tip) with a low rate of elong... |
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Characterization of the plasma membrane H+-ATPase in the liverwort Marchantia polymorpha.
Plant Physiol. 159(2) , 826-34, (2012) The plasma membrane H(+)-ATPase generates an electrochemical gradient of H(+) across the plasma membrane that provides the driving force for solute transport and regulates pH homeostasis and membrane potential in plant cells. Recent studies have demonstrated ... |
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Effects of fusicoccin on ion fluxes in guard cells.
New Phytol. 186(3) , 636-47, (2010) The pharmacology has been further investigated of the two transport systems mediating potassium (rubidium) (K(+)(Rb(+))) release from the guard cell vacuole, responsible, respectively, for the resting efflux and abscisic acid (ABA)-induced transient stimulati... |
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Inhibition of dark-induced stomatal closure by fusicoccin involves a removal of hydrogen peroxide in guard cells of Vicia faba.
Physiol. Plant. 140(3) , 258-68, (2010) Fusicoccin (FC) treatment prevents dark-induced stomatal closure, the mechanism of which is still obscure. By using pharmacological approaches and laser-scanning confocal microscopy, the relationship between FC inhibition of dark-induced stomatal closure and ... |
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Fusicoccin affects cortical microtubule orientation in the isolated epidermis of sunflower hypocotyls.
Plant Biol. (Stuttg.) 13(1) , 201-8, (2011) Epidermal peels isolated from sunflower hypocotyls provide a convenient model to study the relationship between cortical microtubule orientation and strain rate. Extension of peels can be modulated using chemical treatment and mechanical stress, i.e., by addi... |
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Fusicoccin-A selectively induces apoptosis in tumor cells after interferon-alpha priming.
Cancer Lett. 293(2) , 198-206, (2010) Active small molecules have a high potential for the development into new anti-cancer drugs. Here we analysed the effect of the natural occurring fusicoccanes, Fusicoccin-A (FC), Ophiobolin-A (OPH-A) and Ophiobolin-I (OPH-I) on various tumor cell lines. Both ... |
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Molecular breeding of a fungus producing a precursor diterpene suitable for semi-synthesis by dissection of the biosynthetic machinery.
PLoS ONE 7(8) , e42090, (2012) Many clinically useful pharmaceuticals are semi-synthesized from natural products produced by actinobacteria and fungi. The synthetic protocols usually contain many complicated reaction steps and thereby result in low yields and high costs. It is therefore im... |
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Involvement of plasma membrane H+-ATPase in anoxic elongation of stems in pondweed (Potamogeton distinctus) turions.
New Phytol. 190(2) , 421-30, (2011) • Pondweed (Potamogeton distinctus) turions can elongate in the absence of O(2). Alcoholic fermentation serves to produce energy for anoxic elongation via the breakdown of starch stored in cells. However, the mechanism of cell growth during anoxic elongation ... |
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Activation of NF-κB signalling by fusicoccin-induced dimerization.
Proc. Natl. Acad. Sci. U. S. A. 110(5) , E377-86, (2013) Chemically induced dimerization is an important tool in chemical biology for the analysis of protein function in cells. Here we report the use of the natural product fusicoccin (FC) to induce dimerization of 14-3-3-fused target proteins with proteins tagged t... |