Ethyl 1H-indole-3-carboxylate

Ethyl 1H-indole-3-carboxylate Structure
Ethyl 1H-indole-3-carboxylate structure
Common Name Ethyl 1H-indole-3-carboxylate
CAS Number 776-41-0 Molecular Weight 189.210
Density 1.2±0.1 g/cm3 Boiling Point 342.4±15.0 °C at 760 mmHg
Molecular Formula C11H11NO2 Melting Point 120-124ºC
MSDS Chinese USA Flash Point 160.9±20.4 °C

Synthesis of the aziridinomitosene skeleton by intramolecular Michael addition of alpha-lithioaziridines: an aromatic route featuring deuterium as a removable blocking group.

J. Org. Chem. 69 , 1794-1799, (2004)

A convergent synthetic route to the 1,2-aziridinopyrrolo(1,2-a)indole 34 has been developed. Key features of this route include the deuterium kinetic isotope effect to block undesired indole lithiation during tin-lithium exchange from 27a to 30a, the intramol...