2-Methylcyclopentane-1,3-dione

2-Methylcyclopentane-1,3-dione Structure
2-Methylcyclopentane-1,3-dione structure
Common Name 2-Methylcyclopentane-1,3-dione
CAS Number 765-69-5 Molecular Weight 112.127
Density 1.1±0.1 g/cm3 Boiling Point 218.0±23.0 °C at 760 mmHg
Molecular Formula C6H8O2 Melting Point 212-215 °C(lit.)
MSDS Chinese USA Flash Point 78.5±19.6 °C

Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.

J. Med. Chem. 48 , 2906-15, (2005)

Carboxylesterases (CE) are ubiquitous enzymes responsible for the metabolism of xenobiotics. Because the structural and amino acid homology among esterases of different classes, the identification of selective inhibitors of these proteins has proved problemat...

Enantiomeric deoxycholic acid: total synthesis, characterization, and preliminary toxicity toward colon cancer cell lines.

J. Org. Chem. 72(24) , 9298-307, (2007)

Deoxycholic acid (DCA) is an endogenous secondary bile acid implicated in numerous pathological conditions including colon cancer formation and progression and cholestatic liver disease. DCA involvement in these disease processes results partly from its abili...

Dyotropic rearrangements of fused tricyclic β-lactones: application to the synthesis of (-)-curcumanolide A and (-)-curcumalactone.

J. Am. Chem. Soc. 134(32) , 13348-56, (2012)

Dyotropic rearrangements of fused, tricyclic β-lactones are described that proceed via unprecedented stereospecific, 1,2-acyl migrations delivering bridged, spiro-γ-butyrolactones. A unique example of this dyotropic process involves a fused bis-lactone posses...