OM99-2 trifluoroacetate salt
OM99-2 trifluoroacetate salt structure
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Common Name | OM99-2 trifluoroacetate salt | ||
|---|---|---|---|---|
| CAS Number | 314266-76-7 | Molecular Weight | 892.99200 | |
| Density | 1.311g/cm3 | Boiling Point | 1322.4ºC at 760mmHg | |
| Molecular Formula | C41H64N8O14 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 753.6ºC | |
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Inhibitors of Alzheimer's BACE-1 with 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridine structure.
Arch. Pharm. Res. 38(4) , 456-69, (2015) β-site amyloid precursor protein cleaving enzyme (BACE-1) is a validated target for Alzheimer therapy due to its distinctive role in pathogenesis of AD. In the present contribution, a series of new 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyrid... |
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Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor.
Science 290 , 150, (2000) Memapsin 2 (beta-secretase) is a membrane-associated aspartic protease involved in the production of beta-amyloid peptide in Alzheimer's disease and is a major target for drug design. We determined the crystal structure of the protease domain of human memapsi... |
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Chlamydia trachomatis prevalence and chlamydial/HPV co-infection among HPV-unvaccinated young Italian females with normal cytology.
Hum. Vaccin. Immunother. 11(1) , 270-6, (2015) Infections caused by Chlamydia trachomatis (Ct) and human papillomavirus (HPV) are the two main sexually transmitted infections; however, epidemiological data on Ct prevalence and Ct/HPV co-infection in Italy are scant. This study aimed at estimating the prev... |
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Design of potent inhibitors for human brain memapsin (β-secretase). Ghosh, A.K.
J. Am. Chem. Soc. 122 , 3522, (2000)
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