3-NITROBENZAMIDE
3-NITROBENZAMIDE structure
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Common Name | 3-NITROBENZAMIDE | ||
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| CAS Number | 645-09-0 | Molecular Weight | 166.13400 | |
| Density | 1.431g/cm3 | Boiling Point | 310 - 315ºC | |
| Molecular Formula | C7H6N2O3 | Melting Point | 140-143 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 145.852ºC | |
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Novel inhibitors of poly(ADP-ribose) synthetase.
Biochem. J. 185 , 775-777, (1980) In a search for new inhibitors of the nuclear enzyme poly(ADP-ribose) synthetase, it was found that various benzamides substituted in the 3-position were the most inhibitory compounds found to date. Two of the benzamides, 3-aminobenzamide and 3-methoxybenzami... |
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Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis.
J. Biol. Chem. 257(11) , 6084-8, (1982) We have shown previously that alloxan and streptozotocin, two major diabetogenic agents, cause DNA strand breaks in rat pancreatic islets and stimulate nuclear poly(ADP-ribose) synthetase, thereby depleting intracellular NAD level and inhibiting proinsulin sy... |
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