N-Octanoyl-N-methyl-D-glucamine
N-Octanoyl-N-methyl-D-glucamine structure
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Common Name | N-Octanoyl-N-methyl-D-glucamine | ||
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| CAS Number | 85316-98-9 | Molecular Weight | 321.41 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 581.8±50.0 °C at 760 mmHg | |
| Molecular Formula | C15H31NO6 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 305.6±30.1 °C | |
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LitR is a repressor of syp genes and has a temperature-sensitive regulatory effect on biofilm formation and colony morphology in Vibrio (Aliivibrio) salmonicida.
Appl. Environ. Microbiol. 80(17) , 5530-41, (2014) Vibrio (Aliivibrio) salmonicida is the etiological agent of cold water vibriosis, a disease in farmed Atlantic salmon (Salmo salar) that is kept under control due to an effective vaccine. A seawater temperature below 12°C is normally required for disease deve... |
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Roflumilast partially reverses smoke-induced mucociliary dysfunction.
Respir. Res. 16 , 135, (2015) Phosphodiesterases (PDEs) break down cAMP, thereby regulating intracellular cAMP concentrations and diffusion. Since PDE4 predominates in airway epithelial cells, PDE4 inhibitors can stimulate Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by incr... |
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Heterologous Expression of Mannanase and Developing a New Reporter Gene System in Lactobacillus casei and Escherichia coli.
PLoS ONE 10 , e0142886, (2015) Reporter gene systems are useful for studying bacterial molecular biology, including the regulation of gene expression and the histochemical analysis of protein products. Here, two genes, β-1,4-mannanase (manB) from Bacillus pumilus and β-glucuronidase (gusA)... |
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Blending effects on adsorption and micellization of different membrane protein solubilizers: a thermodynamic study on three mixed systems of CHAPS with MEGA-8, -9 and -10 in pH 7.2 phosphate buffer solution.
Colloids Surf. B Biointerfaces 45(2) , 90-103, (2005) By means of surface tension measurement (Wilhelmy method), micellization and adsorbed film formation were investigated for three combinations of mixed surfactant systems, all of which are used for solubilizing membrane proteins: a typical zwitterionic surfact... |
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Purification and photoaffinity labeling of the I-Ak histocompatibility molecule.
J. Immunol. Methods 135(1-2) , 233-45, (1990) Photoaffinity labeling was used to evaluate optimal conditions for purification of I-A k histocompatibility molecules in functionally active form. We assessed the biological activity of I-A k primarily by its binding of the hen egg-white lysozyme (HEL) peptid... |
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Gadolinium(III) Complexes with N-Alkyl-N-methylglucamine Surfactants Incorporated into Liposomes as Potential MRI Contrast Agents.
Bioinorg. Chem. Appl. 2015 , 942147, (2015) Complexes of gadolinium(III) with N-octanoyl-N-methylglucamine (L8) and N-decanoyl-N-methylglucamine (L10) with 1 : 2 stoichiometry were synthesized and characterized by elemental analysis, electrospray ionization-tandem mass spectrometry (ESI-MS), infrared (... |
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Detergents stabilize the conformation of phosphodiesterase 6.
Biochemistry 50(44) , 9520-31, (2011) Membrane-bound phosphodiesterase 6 (PDE6) plays an important role in visual signal transduction by regulating cGMP levels in rod photoreceptor cells. Our understanding of PDE6 catalysis and structure suffers from inadequate characterization of the α and β sub... |
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The structures of 1-deoxy-(N-methyloctanamido)-D-glucitol (MEGA-8) and 1-deoxy-(N-methylundecanamido)-D-glucitol (MEGA-11).
Acta Crystallogr. B 45 ( Pt 4) , 447-52, (1989) 1-Deoxy-(N-methyloctanamido)-D-glucitol, C15H31NO6 (MEGA-8), crystallizes in space group P2(1)2(1)2(1), Mr = 321.4, a = 4.865 (1), b = 9.186 (3), c = 39.097 (9) A, V = 1747.24 A3, Z = 4, Dx = 1.22 Mg m-3, lambda (Cu K alpha) = 1.5418 A, mu = 0.78 mm-1, F(000)... |
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3-O-alkyl-D-glucose derivatives induce fruit bodies of Pleurotus ostreatus.
Mycol. Res. 109(Pt 3) , 374-6, (2005) Amphipathic glucose derivatives 3-O-octyl- and 3-O-decyl-D-glucose were synthesized, and the ability to induce fruit bodies on Pleurotus ostreatus was examined. Surfactants such as CHAPS, CHAPSO, MEGA-8, MEGA-9, and MEGA-10 were also assayed. The result was t... |
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The usefulness of sugar surfactants as solubilizing agents in parenteral formulations.
Int. J. Pharm. 252 , 61-71, (2003) The usefulness of sugar surfactants as solubilizing agents was assessed and compared to commercial polyoxyethylene-based surfactants. The sugar surfactants examined comprised of monosaccharides or disaccharides with alkyl chains ranging from C(8) to C(12). Ea... |