(S)-Crizotinib

(S)-Crizotinib Structure
(S)-Crizotinib structure
Common Name (S)-Crizotinib
CAS Number 1374356-45-2 Molecular Weight 450.33700
Density N/A Boiling Point N/A
Molecular Formula C21H22Cl2FN5O Melting Point N/A
MSDS Chinese USA Flash Point N/A

Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1.

Onco. Targets Ther. 8 , 3649-64, (2015)

Inhibition of the nucleotide pool sanitizing enzyme MTH1 causes extensive oxidative DNA damages and apoptosis in cancer cells and hence may be used as an anticancer strategy. As natural products have been a rich source of medicinal chemicals, in the present s...