SB590885

SB590885 Structure
SB590885 structure
Common Name SB590885
CAS Number 405554-55-4 Molecular Weight 453.536
Density 1.3±0.1 g/cm3 Boiling Point 691.1±55.0 °C at 760 mmHg
Molecular Formula C27H27N5O2 Melting Point N/A
MSDS USA Flash Point 371.8±31.5 °C

ERBB3 is required for metastasis formation of melanoma cells.

Oncogenesis 3 , e110, (2014)

Melanoma is curable when it is at an early phase but is lethal once it becomes metastatic. The recent development of BRAF(V600E) inhibitors (BIs) showed great promise in treating metastatic melanoma, but resistance developed quickly in the treated patients, a...