H-Ala-D-Glu(Lys-D-Ala-D-Ala-OH)-OH
H-Ala-D-Glu(Lys-D-Ala-D-Ala-OH)-OH structure
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Common Name | H-Ala-D-Glu(Lys-D-Ala-D-Ala-OH)-OH | ||
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| CAS Number | 2614-55-3 | Molecular Weight | 488.53500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H36N6O8 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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TMEFF2 deregulation contributes to gastric carcinogenesis and indicates poor survival outcome.
Clin. Cancer Res. 20(17) , 4689-704, (2014) The role and clinical implication of the transmembrane protein with EGF and two follistatin motifs 2 (TMEFF2) in gastric cancer is poorly understood.Gene expression profile analyses were performed and Gene Set Enrichment Analysis (GSEA) was used to explore it... |
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Synthesis of the L-alanyl-L-alanine cross-bridge of Enterococcus faecalis peptidoglycan.
J. Biol. Chem. 277 , 45935-45941, (2002) The enzymatic synthesis of the complete l-alanyl(1)-l-alanine(2) side chain of the peptidoglycan precursors of Enterococcus faecalis was obtained in vitro using purified enzymes. The pathway involved alanyl-tRNA synthetase and two ligases, BppA1 and BppA2, th... |
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Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins.
Proc. Natl. Acad. Sci. U. S. A. 104 , 8761-8766, (2007) Peptidoglycan recognition proteins (PGRPs) are highly conserved pattern-recognition molecules of the innate immune system that bind bacterial peptidoglycans (PGNs), which are polymers of alternating N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM) cro... |
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Affinity chromatography of glycopeptide antibiotics.
J. Chromatogr. A. 392 , 225-238, (1987) An affinity support was designed to facilitate the isolation and purification of glycopeptide antibiotics by mimicking their known affinity for the bacterial cell wall. Members of this class of antibiotics inhibit peptidoglycan biosynthesis by specifically bi... |
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Homogenous rabbit 7S anti-IgG with antibody specificity for peptidoglycan.
J. Exp. Med. 138(5) , 1184-1193, (1973) The relationship between 7S anti-IgG and antibodies to streptococcal cell wall peptidoglycan was examined for four streptococcal Group C antisera. Homogeneous 7S anti-IgG components in these sera were isolated by means of an IgG immunoadsorbent column. For tw... |
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Detection of antibodies to bacterial cell wall peptidoglycan in human sera.
J. Immunol. 117 , 23-26, (1976) A radioimmunoassay has been developed for the measurement of antibodies to peptidoglycan in human sera including patients with rheumatic fever and juvenile rheumatoid arthritis. The assay is based on the percentage of binding of the hapten 125I-L-Ala-gamma-d-... |
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Measurement of peptidoglycan antibodies by a radioimmunoassay.
Z. Immunitatsforsch. Exp. Klin. Immunol. 149 , 168-178, (1975) Staphylococcus epidermidis peptidoglycans solubilized by sonication or lysozyme digestion, and synthetic peptidoglycan analogs such as HSA-carboxymethyl-Gly-L-Ala-L-Ala-D-Ala-D-Ala (HSA-pentapeptide) or L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala (pentapeptide) have ... |
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Detection of Staphylococcus aureus cell walls by enzyme-linked immunoassay using antibodies prepared from a semi-synthetic peptidoglycan precursor.
Analyst 137(5) , 1130-6, (2012) The peptidoglycan layer of Staphylococcus aureus contains a (Gly)(5) cross-link which is not found in other bacteria, and which could be used to develop a specific immunoassay for detection of S. aureus in MRSA infections. A semi-synthetic route was used to p... |
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Silencing of glycopeptide resistance in Enterococcus faecalis BM4405 by novobiocin.
Antimicrob. Agents Chemother. 49 , 1419-1425, (2005) Enterococcus faecalis BM4405-1, a susceptible derivative of the VanE-type vancomycin-resistant E. faecalis strain BM4405, was obtained after growth in the presence of novobiocin, an inhibitor of the GyrB subunit of DNA gyrase. In contrast to findings for BM44... |
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Immunochemistry of a synthetic peptidoglycan-precursor pentapeptide.
Biochemistry 12 , 3387-3394, (1973)
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