(S)-ATPO
(S)-ATPO structure
|
Common Name | (S)-ATPO | ||
|---|---|---|---|---|
| CAS Number | 252930-37-3 | Molecular Weight | 322.25 | |
| Density | N/A | Boiling Point | 569.2±60.0 °C | |
| Molecular Formula | C11H19N2O7P | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
|
Synthesis and pharmacology of highly selective carboxy and phosphono isoxazole amino acid AMPA receptor antagonists.
J. Med. Chem. 39 , 1682-1691, (1996) (RS)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA, 5) and the selective AMPA receptor antagonist (RS)-2-amino-3-[3-(carboxymethoxy)-5-methyl-4-isoxazolyl]propionic acid (AMOA, 7) have been used as leads for the design and synthesis of a num... |
|
|
Resolution, absolute stereochemistry, and enantiopharmacology of the GluR1-4 and GluR5 antagonist 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.
Chirality 11 , 752-9, (1999) The phosphono amino acid, (RS)-2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl+ ++]propio nic acid (ATPO), is a structural hybrid between the NMDA antagonist (RS)-2-amino-7-phosphonoheptanoic acid (AP7) and the AMPA and GluR5 agonist, (RS)-2-amino-3... |
|
|
Antagonist properties of a phosphono isoxazole amino acid at glutamate R1-4 (R,S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid receptor subtypes.
Mol. Pharmacol. 53 , 590-6, (1998) The activity of the (R, S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist, (R,S) -2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl] propionic acid (ATPO), at recombinant ionotropic glutamate receptors (GluRs) was... |
|
|
High prevalence of subclinical hypothyroidism and nodular thyroid disease in patients on hemodialysis.
Hemodial. Int. 20 , 31-Jul, (2016) Chronic kidney disease has been known to affect thyroid hormone metabolism. Low serum levels of T3 and T4 are the most remarkable laboratorial findings. A high incidence of goiter and nodules on thyroid ultrasonography has been reported in patients with end-s... |