4-Acetamidobenzoic acid
4-Acetamidobenzoic acid structure
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Common Name | 4-Acetamidobenzoic acid | ||
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| CAS Number | 556-08-1 | Molecular Weight | 179.17 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 439.6±28.0 °C at 760 mmHg | |
| Molecular Formula | C9H9NO3 | Melting Point | 259-262 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 219.7±24.0 °C | |
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Comparison of xenobiotic metabolizing enzyme activities in ex vivo human skin and reconstructed human skin models from SkinEthic.
Arch. Toxicol. 88(9) , 1681-1694, (2014) Skin function is not limited to a physical barrier. According to its total surface area, it is also considered as an extra-hepatic metabolizing organ. In vitro engineered human skins have been developed to replace limited ex vivo normal human skin samples (NH... |
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Regioselective carboxylation of catechol by 3,4-dihydroxybenzoate decarboxylase of Enterobacter cloacae P.
Biotechnol. Lett. 32(5) , 701-5, (2010) 3,4-Dihydroxybenzoate decarboxylase in Enterobacter cloacae P241 was induced by adding 3,4-dihydroxybenzoic acid, 3-hydroxybenzoic acid, 3,4,5-trihydroxybenzoic acid or 4-acetamidobenzoic acid to the culture medium. After stabilizing the enzyme activity by ad... |
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Effects of butylated hydroxyanisole and butylated hydroxytoluene on DNA adduct formation and arylamine N-acetyltransferase activity in human bladder tumour cells.
J. Appl. Toxicol. 22(1) , 37-44, (2002) In this study, butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) were used to determine the inhibition of arylamine N-acetyltransferase (NAT) activity and DNA adduct formation in human bladder tumour cell line T-24. The activity of NAT was mea... |
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Benzoic acid and pyridine derivatives as inhibitors of Trypanosoma cruzi trans-sialidase.
Bioorg. Med. Chem. 15 , 2106-19, (2007) Benzoic acid and pyridine derivatives inhibit recombinant trans-sialidase from Trypanosoma cruzi with I50 values between 0.4 and 1mM. The best compounds, 4-acetylamino-3-hydroxymethylbenzoic acid and 5-acetylamino-6-aminopyridine-2-carboxylic acid, provide ne... |
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Analysis of N-benzoyl-L-tyrosyl-p-aminobenzoic acid (bentiromide) metabolites in urine by ion-pair high-performance liquid chromatography.
J. Chromatogr. A. 338(2) , 377-88, (1985) A high-performance liquid chromatographic method is described for the analysis of bentiromide metabolites in urine. The procedure involves no more than direct injection of the diluted urine sample, obviating the need for an extraction step or an internal stan... |
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Simultaneous determination of p-aminobenzoic acid and its metabolites in the urine of volunteers, treated with p-aminobenzoic acid sunscreen formulation.
J. Pharm. Biomed. Anal. 43(4) , 1430-6, (2007) p-Aminobenzoic acid (PABA) and its metabolites (p-aminohippuric acid, p-acetamidobenzoic acid, and p-acetamidohippuric acid) were detected using high-performance liquid chromatography with an electrochemical (carbon paste) detector (HPLC-ECD). For direct curr... |
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Inhibition of Pneumocystis carinii dihydropteroate synthetase by para-acetamidobenzoic acid: possible mechanism of action of isoprinosine in human immunodeficiency virus infection.
Antimicrob. Agents Chemother. 37(6) , 1227-31, (1993) Isoprinosine has been reported to decrease progression to AIDS, primarily by preventing Pneumocystis carinii pneumonia (PCP), in human immunodeficiency virus-infected patients, but the mechanism of action is unknown. para-Acetamidobenzoic acid (PAcBA), one co... |
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Quantification of benzocaine and its metabolites in channel catfish tissues and fluids by HPLC.
J. Pharm. Biomed. Anal. 16(1) , 69-75, (1997) Methods for extraction and gradient HPLC quantification were developed for benzocaine (BZ) and three of its metabolites to be used in conjunction with a reverse isotope technique. The metabolites were p-aminobenzoic acid (PABA), acetyl-p-aminobenzoic acid (Ac... |
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[Aminobenzoic acid derivatives as specific inhibitors of cyclic nucleotide phosphodiesterase in the rat uterus].
Ukr. Biokhim. Zh. 62(1) , 97-101, (1990) It is shown, that p-aminobenzoic acid and its derivatives (p-acetylaminobenzoic acid and p-aminobenzoic acid hydrazide) in the concentration of 10(-6) M are the potent inhibitors (40% below the control specimens) of the phosphodiesterase activity of cyclic nu... |
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Inosiplex: metabolism and excretion of the dimethylaminoisopropanol and p-acetamidobenzoic acid components in rhesus monkeys.
Drug Metab. Dispos. 12(2) , 199-203, (1984) The principal excretion products derived from radiolabeled N,N-dimethylaminoisopropanol (Dip) and p-acetamidobenzoic acid (PAcBA) components of inosiplex (Isoprinosine) were identified and quantified in urine following single iv and oral administration of the... |