Famciclovir

Famciclovir Structure
Famciclovir structure
Common Name Famciclovir
CAS Number 104227-87-4 Molecular Weight 321.332
Density 1.4±0.1 g/cm3 Boiling Point 550.2±60.0 °C at 760 mmHg
Molecular Formula C14H19N5O4 Melting Point 102-104°C
MSDS Chinese USA Flash Point 286.6±32.9 °C

Dissolution testing and potentiometric determination of famciclovir in pure, dosage forms and biological fluids.

Bioelectrochemistry 89 , 26-33, (2013)

The performance characteristics of two new plastic membrane ion selective electrodes (ISEs) used for the determination of famciclovir (Fcv) based on the ion associate of Fcv with phosphotungstic acid (PTA) or phosphomolybdic acid (PMA) are described. Differen...

Pediatric herpes simplex of the anterior segment: characteristics, treatment, and outcomes.

Ophthalmology 119(10) , 2003-8, (2012)

To describe the clinical characteristics, treatment, and outcomes of herpes simplex virus (HSV) infections of the cornea and adnexae to raise awareness and to improve management of this important eye disease in children.Retrospective case series.Fifty-three p...

Estimates of the pharmacokinetics of famciclovir and its active metabolite penciclovir in young Asian elephants (Elephas maximus).

Am. J. Vet. Res. 73(12) , 1996-2000, (2012)

To determine plasma pharmacokinetics of penciclovir following oral and rectal administration of famciclovir to young Asian elephants (Elephas maximus).6 healthy Asian elephants (5 females and 1 male), 4.5 to 9 years old and weighing 1,646 to 2,438 kg.Famciclo...

Varicella-zoster virus infection and nummular headache: a possible association with epicranial neuralgia.

Intern. Med. 51(17) , 2439-41, (2012)

A nummular headache (NH) is a type of primary headache that results from cranial neuralgia without a known cause. We herein report the case of a woman who suffered two episodes of focal headache in the left parietal area with identical characteristics that we...

Oral antiviral therapy for prevention of genital herpes outbreaks in immunocompetent and nonpregnant patients.

Cochrane Database Syst. Rev. 8 , CD009036, (2014)

Genital herpes is caused by herpes simplex virus 1 (HSV-1) or 2 (HSV-2). Some infected people experience outbreaks of genital herpes, typically, characterized by vesicular and erosive localized painful genital lesions.To compare the effectiveness and safety o...

Topical and systemic therapies for oral and perioral herpes simplex virus infections.

J. Calif. Dent. Assoc. 41(4) , 259-62, (2013)

Oral and perioral herpes simplex virus (HSV) infections in healthy individuals often present with signs and symptoms that are clearly recognized by oral health care providers (OHCPs). Management of these infections is dependent upon a variety of factors and s...

Image diagnosis: Ramsay Hunt syndrome.

Perm. J. 16(4) , 51-2, (2012)

Emerging concepts in the management of acute retinal necrosis.

Br. J. Ophthalmol. 97(5) , 545-52, (2013)

Acute retinal necrosis (ARN), also known as Kirisawa-type uveitis, is an uncommon condition caused by infection of the retina by one of the herpes family of viruses, most typically varicella zoster virus or herpes simplex virus and less commonly cytomegalovir...

Famciclovir as an antiviral agent for a patient with acute renal failure.

Int. J. Clin. Pharm. 35(2) , 173-5, (2013)

Acyclovir is a widely administered medication for viral infection but is well known for its nephrotoxicity. To date, few studies regarding the safety of alternative antiviral agents have been reported. This study reports the case of a patient with renal dysfu...

Famciclovir for recurrent herpes-associated erythema multiforme: a series of three cases.

J. Am. Acad. Dermatol. 71(4) , e146-7, (2014)