Coprostanone
Coprostanone structure
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Common Name | Coprostanone | ||
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| CAS Number | 566-88-1 | Molecular Weight | 386.654 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 452.9±13.0 °C at 760 mmHg | |
| Molecular Formula | C27H46O | Melting Point | 127-131ºC | |
| MSDS | Chinese USA | Flash Point | 219.3±12.1 °C | |
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In vitro modulation of rat adipocyte ghost membrane fluidity by cholesterol oxysterols.
Experientia 51(7) , 731-7, (1995) The effects of cholesterol and cholesterol-derived oxysterols (cholestanone, cholestenone, coprostanone and epicoprostanol) on adipocyte ghost membrane fluidity were studied using a fluorescence depolarization method. The fluorescence anisotropy of the treate... |
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Diet, nutrition intake, and metabolism in populations at high and low risk for colon cancer. Metabolism of neutral sterols.
Am. J. Clin. Nutr. 40(4 Suppl) , 931-6, (1984) Cholesterol and its metabolites, together with bile acids, are implicated as risk factors in the genesis and progression of colon cancer. This study was designed to determine differences in the neutral sterol composition of stools from four different populati... |
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Potentiation of beta-adrenoceptor agonist mediated-lipolysis by cholesterol-derived oxysterols.
Biochem. Mol. Biol. Int. 35(6) , 1349-58, (1995) Cholesterol-derived oxysterols such as cholestanol, cholestanone and coprostanone were able to potentiate epinephrine-induced lipolysis in intact rat adipocytes but not cholesterol. The relative potency of the oxysterols followed the sequence: cholestanone > ... |
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Studies on the sterol-binding capacity of human pancreatic elastase 1.
Gastroenterology 100(3) , 768-74, (1991) In previous studies we isolated human pancreatic elastase 1 from intestinal lavage fluids, where it was found to be part of a complex whose major component was cholesterol. The present study involves the isolation and characterization of this elastase 1-stero... |
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Dietary fiber supplementation and fecal bile acids, neutral steroids and divalent cations in rats.
J. Nutr. 117(12) , 2009-15, (1987) Young adult rats were fed ad libitum for 4 wk on defined diets containing either no fiber, 10% levels of insoluble fiber sources [cellulose, wheat bran, alfalfa, mixed fibers (Fibyrax)], 5% levels of soluble fiber sources [pectin, guar gum, psyllium (Metamuci... |
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Genotoxicity of two fecal steroids in murine colonic epithelium assessed by the sister chromatid exchange technique.
Mutagenesis 2(6) , 441-4, (1987) Two components of human feces are known to induce nuclear anomalies in mice when applied intrarectally, but to be nonmutagenic in Salmonella. We have tested these two compounds for their ability to induce sister chromatid exchanges in the colonic epithelium o... |
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Intestinal steroids in rats are influenced by the structural parameters of pectin.
J. Nutr. Biochem. 15(4) , 196-205, (2004) We investigated the effects of pectin with different degrees of methylation (34.5, 70.8, and 92.6%, respectively) on the composition and concentration of intestinal and fecal bile acids and neutral sterols in conventional and germfree rats. Diets containing 6... |
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Faecal steroid excretion in humans is affected by calcium supplementation and shows gender-specific differences.
Eur. J. Nutr. 48(1) , 22-30, (2009) Previous human studies on the effect of dietary calcium supplementation on faecal excretion of bile acids (BA) and faecal water concentrations of animal neutral sterols (NSt, cholesterol and its metabolites) lack detailed information about single BA and NSt.W... |
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Loss of tritium from coprostanone derived from [1,2(n)-3H]cholesterol or [7(n)-3H]cholesterol.
J. Lipid Res. 21(4) , 480-4, (1980) After oral administration of a mixture of [1,2(n)-3H]cholesterol and [4-14C]cholesterol to a baboon, fecal coprostanone had a 46% lower 3H/14C ratio than the dose administered. Loss of 3H by enolization of the 3-ketone could account for the decrease in 3H/14C... |
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Effects of gamma-irradiated fats on plasma lipid concentrations and hepatic cholesterol metabolism in rats.
Ann. Nutr. Metab. 45(4) , 152-8, (2001) Currently, there is a growing need for food irradiation that is effective in food preservation and quality improvement. Accordingly, this study was designed to observe the effects of gamma-irradiated dietary fat on plasma lipid concentrations and hepatic chol... |