Thenoyltrifluoroacetone
Thenoyltrifluoroacetone structure
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Common Name | Thenoyltrifluoroacetone | ||
|---|---|---|---|---|
| CAS Number | 326-91-0 | Molecular Weight | 222.18 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 227.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C8H5F3O2S | Melting Point | 40-44 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 111.7±0.0 °C | |
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Screening of stabilizers for LC-MS/MS analysis of clevidipine and its primary metabolite in dog whole blood.
Bioanalysis 7 , 1457-69, (2015) Clevidipine is an ester-containing antihypertensive agent that undergoes rapid hydrolysis in blood. A reliable stabilizer cocktail containing citric acid and ascorbic acid was established and the LC-MS/MS method was validated for simultaneous determination of... |
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Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion.
Sci. Signal. 8 , ra80, (2015) Survivin promotes cell division and suppresses apoptosis in many human cancers, and increased abundance correlates with metastasis and poor prognosis. We showed that a pool of survivin that localized to the mitochondria of certain tumor cell lines enhanced th... |
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Mitochondrial-derived reactive oxygen species play a vital role in the salicylic acid signaling pathway in Arabidopsis thaliana.
PLoS ONE 10 , e0119853, (2015) Plant mitochondria constitute a major source of ROS and are proposed to act as signaling organelles in the orchestration of defense response. At present, the signals generated and then integrated by mitochondria are still limited. Here, fluorescence technique... |
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Family with sequence similarity 5, member C (FAM5C) increases leukocyte adhesion molecules in vascular endothelial cells: implication in vascular inflammation.
PLoS ONE 9(9) , e107236, (2014) Identification of the regulators of vascular inflammation is important if we are to understand the molecular mechanisms leading to atherosclerosis and consequent ischemic heart disease, including acute myocardial infarction. Gene polymorphisms in family with ... |
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Self-limiting adsorption of Eu³⁺ on the surface of rod-shape anatase TiO₂ nanocrystals and post-synthetic sensitization of the europium-based emission.
J. Colloid. Interface Sci. 459 , 63-9, (2015) The surface of oleic acid stabilized rod-shape anatase TiO2 nanocrystals was modified by adsorption of Eu(3+) ions. The Eu(3+) attachment showed Langmuir adsorption behavior, thus the loading of Eu(3+) could be controlled precisely up to surface saturation co... |
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Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced enteritis.
Hum. Exp. Toxicol. 33(10) , 1051-65, (2014) The efficacy of methotrexate (MTX), a widely used chemotherapeutic drug, is limited by its gastrointestinal toxicity and the mechanism of which is not clear. The present study investigates the possible role of mitochondrial damage in MTX-induced enteritis. Sm... |
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Iron oxide functionalized graphene oxide as an efficient sorbent for dispersive micro-solid phase extraction of sulfadiazine followed by spectrophotometric and mode-mismatched thermal lens spectrometric determination.
Talanta 147 , 561-8, (2015) A simple and rapid dispersive micro-solid phase extraction (DMSPE) combined with mode-mismatched thermal lens spectrometry as well as fiber optic linear array spectrophotometry was developed for the separation, extraction and determination of sulfadiazine. Gr... |
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Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis.
Toxicol. Sci. 143(1) , 81-96, (2014) Rotenone, a common pesticide and inhibitor of mitochondrial complex I, induces loss of dopaminergic neurons and consequential aspects of Parkinson's disease (PD). However, the exact mechanism of rotenone neurotoxicity is not fully elucidated. Here, we show th... |
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Reactive oxygen species are generated by the respiratory complex II--evidence for lack of contribution of the reverse electron flow in complex I.
FEBS J. 280(3) , 927-38, (2013) Succinate-driven oxidation via complex II (CII) may have a significant contribution towards the high rates of production of reactive oxygen species (ROS) by mitochondria. Here, we show that the CII Q site inhibitor thenoyltrifluoroacetone (TTFA) blocks succin... |
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Esterase inhibitors as ester-containing drug stabilizers and their hydrolytic products: potential contributors to the matrix effects on bioanalysis by liquid chromatography/tandem mass spectrometry.
Rapid Commun. Mass Spectrom. 26(11) , 1291-304, (2012) Esterase inhibitors are widely used to stabilize ester-containing drugs in biological matrices for quantitative liquid chromatography/tandem mass spectrometry (LC/MS/MS) assays. These co-existing inhibitors could cause matrix effects on bioanalysis and jeopar... |