2-Anthraquinonecarboxylic acid
2-Anthraquinonecarboxylic acid structure
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Common Name | 2-Anthraquinonecarboxylic acid | ||
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| CAS Number | 117-78-2 | Molecular Weight | 252.222 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 518.3±39.0 °C at 760 mmHg | |
| Molecular Formula | C15H8O4 | Melting Point | 287-289 | |
| MSDS | Chinese USA | Flash Point | 281.3±23.6 °C | |
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Detecting multiple cell-secreted cytokines from the same aptamer-functionalized electrode.
Biosens. Bioelectron. 64 , 43-50, (2014) Inflammatory cytokines are secreted by immune cells in response to infection or injury. Quantification of multiple cytokines in parallel may help with disease diagnosis by illuminating inflammatory pathways related to disease onset and progression. This paper... |
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Adsorption state and morphology of anthraquinone-2-carboxylic acid deposited from solution onto the atomically-smooth native oxide surface of Al(111) films studied by infrared reflection absorption spectroscopy, X-ray photoelectron spectroscopy, and atomic force microscopy.
Anal. Sci. 24(3) , 313-20, (2008) The adsorption state and morphology of anthraquinone-2-carboxylic acid (AQ-2-COOH) deposited from acetone solutions (0.02 - 1.00 mg ml(-1)) onto atomically-smooth native oxide surfaces of Al(111) films were investigated by infrared reflection absorption spect... |
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Prolidase as a prodrug converting enzyme. II. Synthesis of proline analogue of anthraquinone-2-carboxylic acid and its susceptibility to the action of prolidase.
Rocz. Akad. Med. Bialymst. 43 , 201-9, (1998) The feasibility to targeting prolidase as an antineoplastic prodrug--converting enzyme has been examined. The synthesis of proline analogue of anthraquinone-2-carboxylic acid (potential antineoplastic agent) conjugated through imido-bond (potential target for... |
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Possible cause of G-C-->C-G transversion mutation by guanine oxidation product, imidazolone.
Chem. Biol. 8(4) , 369-78, (2001) The genome is constantly assaulted by oxidation reactions which are likely to be associated with oxygen metabolism, and oxidative lesions are generated by many types of oxidants. Such genotoxin-induced alterations in the genomic message have been implicated i... |
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Physicochemical characterization of 9,10-anthraquinone 2-carboxylic acid.
J. Pharm. Sci. 82(12) , 1250-4, (1993) The physicochemical properties of 9,10-anthraquinone-2-carboxylic acid (AQCA) were investigated by thermal analysis, powder X-ray diffraction pattern, solubility, and partition coefficient. The chemical structure of AQCA was confirmed by the data from UV, Fou... |
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Pharmacodynamic and pharmacokinetic studies of anthraquinone 2-carboxylic acid on passive cutaneous anaphylaxis in rats.
Res. Commun. Mol. Pathol. Pharmacol. 105(1-2) , 97-103, (1999) The objectives of this study are to describe the inhibitory effect of 9,10-anthraquinone 2-carboxylic acid (AQCA) on IgE-mediated passive cutaneous anaphylaxis (PCA) reaction, and the pharmacokinetics of AQCA. Pharmacodynamic assessments were performed at 0.5... |
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L-proline analogues of anthraquinone-2-carboxylic acid: cytotoxic activity in breast cancer MCF-7 cells and inhibitory activity against topoisomerase I and II.
Pol. J. Pharmacol. 53(3) , 283-7, (2001) A series of proline analogues of anthraquinone-2-carboxylic acid (1-3) were synthesized and evaluated for cytotoxic activity in the cultured breast cancer MCF-7 cells. The concentrations of 1, 2 and 3 needed to inhibit [3H]thymidine incorporation into DNA by ... |
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Cytotoxicity activity of L-proline analogues of anthraquinone-2-carboxylic acid in breast cancer MCF-7 cells.
Folia Histochem. Cytobiol. 39 Suppl 2 , 207-8, (2001) Although prolidase [E.C.3.4.13.9] is found in normal cells, substantially increased levels are found in some neoplastic tissues. Prolidase evokes the ability to hydrolyse the imido-bond of various low molecular weight compounds coupled to L-proline. The synth... |
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Coupled Proton and Electron Transfer: Adsorbed Anthraquinone-2-carboxylic Acid Monolayers. Forster RJ.
J. Electrochem. Soc. 144(4) , 1165-73, (1997)
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