2-methyl-b-naphthothiazole

2-methyl-b-naphthothiazole Structure
2-methyl-b-naphthothiazole structure
Common Name 2-methyl-b-naphthothiazole
CAS Number 2682-45-3 Molecular Weight 199.272
Density 1.3±0.1 g/cm3 Boiling Point 352.7±11.0 °C at 760 mmHg
Molecular Formula C12H9NS Melting Point 95-97 °C(lit.)
MSDS Chinese USA Flash Point 174.0±8.2 °C

New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.

Mol. Pharmacol. 86(3) , 342-57, (2014)

Small-conductance (KCa2) and intermediate-conductance (KCa3.1) calcium-activated K(+) channels are voltage-independent and share a common calcium/calmodulin-mediated gating mechanism. Existing positive gating modulators like EBIO, NS309, or SKA-31 activate bo...