Alpha-Methyl-Gamma-Butyrolactone
Alpha-Methyl-Gamma-Butyrolactone structure
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Common Name | Alpha-Methyl-Gamma-Butyrolactone | ||
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| CAS Number | 1679-47-6 | Molecular Weight | 100.11600 | |
| Density | 1.04g/cm3 | Boiling Point | 78ºC(10 torr) | |
| Molecular Formula | C5H8O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 75ºC | |
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Characterization of the PON1 active site using modeling simulation, in relation to PON1 lactonase activity
Bioorg. Med. Chem. 16 , 7504-9, (2008) Paraoxonase1 (PON1) is a HDL bound enzyme and many of the anti-atherogenic properties of HDL are attributed to PON1. The enzyme precise mechanism of protective action and its endogenous substrate remain elusive. PON1 hydrolyzes organophosphates, arylesters an... |
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Enantioselectivity of alpha-benzyl-alpha-methyl-gamma-butyrolactone-mediated modulation of anticonvulsant activity and GABA(A) receptor function.
J. Pharmacol. Exp. Ther. 309(2) , 677-83, (2004) Alkyl-substituted butyrolactones have both inhibitory and stimulatory effects on GABA(A) receptors. Lactones with small alkyl substitutions at the alpha-position positively modulate the channel, whereas beta-substituted lactones tend to inhibit the GABA(A) re... |
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Sites of reaction of pilocarpine.
J. Am. Soc. Mass Spectrom. 10(3) , 209-16, (1999) Analysis of the sites of reaction of a biologically important compound, pilocarpine, a molecule with imidazole and butyrolactone rings connected by a methylene bridge, has been accomplished in a quadrupole ion trap with the aim of characterizing its structure... |