Hydroxocobalamin
Hydroxocobalamin structure
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Common Name | Hydroxocobalamin | ||
|---|---|---|---|---|
| CAS Number | 13422-51-0 | Molecular Weight | 1346.36 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C62H89CoN13O15P | Melting Point | 200ºC (decomposes) | |
| MSDS | N/A | Flash Point | N/A | |
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Pseudo-blood leak? A hemodialysis mystery.
Clin. Nephrol. 79(4) , 323-5, (2013) Hydroxocobalamin is a treatment for cyanide toxicity with few side effects. We report a case of a hemodialysis patient whose treatment was compromised by hydroxocobalamin interference with the blood leak detector. |
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A patient with an inborn error of vitamin B12 metabolism (cblF) detected by newborn screening.
Pediatrics 132(1) , e257-61, (2013) A neonate, who was found to have an elevated C3/C2 ratio and minimally elevated propionylcarnitine on newborn screening, was subsequently identified as having the rare cblF inborn error of vitamin B12 (cobalamin) metabolism. This disorder is characterized by ... |
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Severe combined immunodeficiency resulting from mutations in MTHFD1.
Pediatrics 131(2) , e629-34, (2013) Folate and vitamin B(12) metabolism are essential for de novo purine synthesis, and several defects in these pathways have been associated with immunodeficiency. Here we describe the occurrence of severe combined immunodeficiency (SCID) with megaloblastic ane... |
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Sodium thiosulfate or hydroxocobalamin for the empiric treatment of cyanide poisoning?
Ann. Emerg. Med. 49(6) , 806-13, (2007) Cyanide poisoning must be seriously considered in victims of smoke inhalation from enclosed space fires; it is also a credible terrorism threat agent. The treatment of cyanide poisoning is empiric because laboratory confirmation can take hours or days. Empiri... |
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Cobalamin C defect presenting with isolated pulmonary hypertension.
Pediatrics 132(1) , e248-51, (2013) Cobalamin C (cblC) defect is the most common inborn error of vitamin B12 metabolism. Clinical features vary as does the severity of the disease. In most cases, the clinical symptoms of cblC defect tend to appear during infancy or early childhood as a multisys... |
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Guidelines for the diagnosis and treatment of cobalamin and folate disorders.
Br. J. Haematol. 166(4) , 496-513, (2014) The clinical picture is the most important factor in assessing the significance of test results assessing cobalamin status because there is no 'gold standard' test to define deficiency. Serum cobalamin currently remains the first-line test, with additional se... |
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[Clinical, biological and therapeutic profile of anemia by vitamin B12 deficiency in the department of hematology of Marrakech (Morocco)].
Bull. Soc. Pathol. Exot. Filiales 106(2) , 83-8, (2013) The aim of this study is to examine retrospectively the clinical, biological and treatment features of anemia by vitamin B12 deficiency in the Hematology department of CHU Mohamed VI Marrakech. We report the results of a retrospective study conducted during s... |
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[Hydroxocobalamin].
Chudoku. Kenkyu. 21(4) , 353-9, (2008)
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Hydroxocobalamin as a cyanide antidote.
Am. J. Ther. 13(2) , 161-5, (2006)
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Atypical glomerulopathy associated with the cblE inborn error of vitamin B₁₂ metabolism.
Pediatr. Nephrol. 28(7) , 1135-9, (2013) The cblE disorder is an inherited disorder of vitamin B12 metabolism that results in elevated levels of homocysteine and decreased methionine in body fluids. Renal complications have been reported in patients with cblC disease, but not in those with cblE dise... |