Dimethyltryptamine
Dimethyltryptamine structure
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Common Name | Dimethyltryptamine | ||
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| CAS Number | 61-50-7 | Molecular Weight | 188.269 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 332.1±25.0 °C at 760 mmHg | |
| Molecular Formula | C12H16N2 | Melting Point | 42-44ºC | |
| MSDS | Chinese USA | Flash Point | 154.7±23.2 °C | |
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Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class.
Toxicol. Lett. 241 , 82-94, (2015) New psychoactive substances (NPS) are not tested for their cytochrome P450 (CYP) inhibition potential before consumption. Therefore, this potential was explored for tryptamine-derived NPS (TDNPS) including alpha-methyl tryptamines (AMTs), dimethyl tryptamines... |
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Biosynthesis of N,N-dimethyltryptamine (DMT) in a melanoma cell line and its metabolization by peroxidases.
Biochem. Pharmacol. 88(3) , 393-401, (2014) Tryptophan (TRP) is essential for many physiological processes, and its metabolism changes in some diseases such as infection and cancer. The most studied aspects of TRP metabolism are the kynurenine and serotonin pathways. A minor metabolic route, tryptamine... |
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Metabolism and disposition of N,N-dimethyltryptamine and harmala alkaloids after oral administration of ayahuasca.
Drug Test. Anal. 4(7-8) , 610-6, (2012) Ayahuasca is an Amazonian psychotropic plant tea obtained from Banisteriopsis caapi, which contains β-carboline alkaloids, chiefly harmine, harmaline and tetrahydroharmine. The tea usually incorporates the leaves of Psychotria viridis or Diplopterys cabrerana... |
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Methodology for and the determination of the major constituents and metabolites of the Amazonian botanical medicine ayahuasca in human urine.
Biomed. Chromatogr. 25(9) , 970-84, (2011) Ayahuasca, also known as caapi or yage among various South American groups, holds a highly esteemed and millennia-old position in these cultures' medical and religious pharmacopeia. There is now an increasing interest in the potential for modern medical appli... |
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Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter.
J. Neural Transm. Gen. Sect. 116(12) , 1591-9, (2009) N,N-dimethyltryptamine (DMT) is a potent plant hallucinogen that has also been found in human tissues. When ingested, DMT and related N,N-dialkyltryptamines produce an intense hallucinogenic state. Behavioral effects are mediated through various neurochemical... |
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Determination of N,N-dimethyltryptamine in Mimosa tenuiflora inner barks by matrix solid-phase dispersion procedure and GC-MS.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 881-882 , 107-10, (2012) N,N-dimethyltryptamine (DMT) is a potent hallucinogen found in beverages consumed in religion rituals and neo-shamanic practices over the world. Two of these religions, Santo Daime and União do Vegetal (UDV), are represented in countries including Australia, ... |
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Health status of ayahuasca users.
Drug Test. Anal. 4(7-8) , 601-9, (2012) Ayahuasca is a psychedelic brew originally used for magico-religious purposes by Amerindian populations of the western Amazon Basin. Throughout the last four decades, the use of ayahuasca spread towards major cities in all regions of Brazil and abroad. This t... |
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Determination of dimethyltryptamine and β-carbolines (ayahuasca alkaloids) in plasma samples by LC-MS/MS.
Bioanalysis 4(14) , 1731-8, (2012) Ayahuasca is a psychoactive plant beverage originally used by indigenous people throughout the Amazon Basin, long before its modern use by syncretic religious groups established in Brazil, the USA and European countries. The objective of this study was to dev... |
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Characterisation of a proposed internet synthesis of N,N-dimethyltryptamine using liquid chromatography/electrospray ionisation tandem mass spectrometry.
J. Chromatogr. A. 1216(33) , 6119-23, (2009) The psychoactive properties of N,N-dimethyltryptamine (DMT) are known to induce altered states of consciousness in humans. These properties attract great interest from clinical, neuroscientific, clandestine and forensic communities. The Breath of Hope Synthes... |
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A possibly sigma-1 receptor mediated role of dimethyltryptamine in tissue protection, regeneration, and immunity.
J. Neural Transm. Gen. Sect. 120(9) , 1295-303, (2013) N,N-dimethyltryptamine (DMT) is classified as a naturally occurring serotonergic hallucinogen of plant origin. It has also been found in animal tissues and regarded as an endogenous trace amine transmitter. The vast majority of research on DMT has targeted it... |