4'-Methylsulphonylacetophenone
4'-Methylsulphonylacetophenone structure
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Common Name | 4'-Methylsulphonylacetophenone | ||
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| CAS Number | 10297-73-1 | Molecular Weight | 198.24 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 385.4±34.0 °C at 760 mmHg | |
| Molecular Formula | C9H10O3S | Melting Point | 126-129 °C(lit.) | |
| MSDS | USA | Flash Point | 242.0±18.3 °C | |
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Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosis-inducing agents.
J. Natl. Cancer Inst. 94(23) , 1745-57, (2002) The cyclooxygenase-2 (COX-2) inhibitor celecoxib is thought to act as a chemopreventive agent by sensitizing cancer cells to apoptotic signals. Other COX-2 inhibitors, such as rofecoxib, are two orders of magnitude less potent than celecoxib at inducing apopt... |
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Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors
Eur. J. Med. Chem. 45 , 6135-8, (2010) Eighteen new 1-N-substituted-3,5-diphenyl-2-pyrazoline derivatives have been synthesized and cyclooxygenase (COX-1 and COX-2) inhibitory activities have been evaluated. The results of these biological assays showed that all of new derivatives are not endowed ... |
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New Antibacterial Agents. II. An Alternate Synthesis of DL-threo-2-Dichloro-acetamido-1-(4-methylsulfonylphenyl)-1, 3-propanediol1. Suter CM, et al.
J. Am. Chem. Soc. 75(17) , 4330-4333, (1953)
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