Methyl acetobromo-α-D-glucuronate

Methyl acetobromo-α-D-glucuronate Structure
Methyl acetobromo-α-D-glucuronate structure
Common Name Methyl acetobromo-α-D-glucuronate
CAS Number 21085-72-3 Molecular Weight 397.173
Density 1.5±0.1 g/cm3 Boiling Point 388.6±42.0 °C at 760 mmHg
Molecular Formula C13H17BrO9 Melting Point 80-110 °C(lit.)
MSDS Chinese USA Flash Point 188.8±27.9 °C

Mitochondrial KATP channel inhibition blunts arrhythmia protection in ischemic exercised hearts.

Am. J. Physiol. Heart Circ. Physiol. 299 , H175-183, (2010)

The mechanisms responsible for anti-arrhythmic protection during ischemia-reperfusion (IR) in exercised hearts are not fully understood. The purpose of this investigation was to examine whether the ATP-sensitive potassium channels in the mitochondria (mito K(...

Glucuronidation of HMR1098 in human microsomes: evidence for the involvement of UGT1A1 in the formation of S-glucuronides.

Drug Metab. Dispos. 31 , 1027-1034, (2003)

HMR1098, a novel KATP-blocking agent, is metabolized to form an S-glucuronide in rat and dog bile. Synthesis of the S-glucuronide metabolite was studied in human liver and kidney microsomes. Recombinant UPD-glucuronosyltransferases (UGTs) were screened for ac...

Single channel studies of the ATP-regulated potassium channel in brain mitochondria.

J. Bioenerg. Biomembr. 41 , 323-334, (2009)

Mitochondrial potassium channels in the brain have been suggested to have an important role in neuroprotection. The single channel activity of mitochondrial potassium channels was measured after reconstitution of the purified inner membrane from rat brain mit...